Antioxidant activity of ethanolic extract of three Selaginella species from Java Island, Indonesia

Abstract. Miftahudin, Hasibuan RS, Chikmawati T. 2019. Antioxidant activity of ethanolic extract of three Selaginella species from Java Island, Indonesia. Biodiversitas 20: 3715-3722. Three Selaginella species, S. ornata, S. plana, and S. willdenowii, from Java Island, Indonesia, have been known to...

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Autores principales:	M Miftahudin, Rini Hasibuan, Tatik Chikmawati
Formato:	article
Lenguaje:	EN
Publicado:	MBI & UNS Solo 2019
Materias:	antioxidant, mda, selaginella, sod Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/daabc79eca794477ba9da0b0f290fece
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spelling	oai:doaj.org-article:daabc79eca794477ba9da0b0f290fece2021-11-21T21:59:05ZAntioxidant activity of ethanolic extract of three Selaginella species from Java Island, Indonesia1412-033X2085-472210.13057/biodiv/d201234https://doaj.org/article/daabc79eca794477ba9da0b0f290fece2019-11-01T00:00:00Zhttps://smujo.id/biodiv/article/view/4385https://doaj.org/toc/1412-033Xhttps://doaj.org/toc/2085-4722Abstract. Miftahudin, Hasibuan RS, Chikmawati T. 2019. Antioxidant activity of ethanolic extract of three Selaginella species from Java Island, Indonesia. Biodiversitas 20: 3715-3722. Three Selaginella species, S. ornata, S. plana, and S. willdenowii, from Java Island, Indonesia, have been known to have antioxidant properties; however, in vivo antioxidant activities of these species have not been reported. This research aimed to evaluate the in vivo antioxidant activity of ethanolic extract of three Selaginella species. The 70% ethanol extract of three Selaginella species at four different doses was administered to mice one day before being treated with oxidative stress. The liver tissue of mice treated with or without oxidative stress was analyzed their lipid peroxidation by measuring MDA concentration and Superoxide Dismutase (SOD) activities. The results showed that there were variations in antioxidant activity among the three Selaginella species. In general, the dose of 0.3 g extract kg-1 BW has been able to reduce lipid peroxidation and increase SOD activity. The administration of S. ornata extract to the mice at 1.2 g extract kg-1 BW reduced the MDA concentration to the lowest level, but the same dose of two other Selaginella extracts caused toxic effects in mice. The antioxidant activities of S. ornata and S. plana were better than that of S. willdenowii extract, and among those species, S. ornata has the best antioxidant activity.M MiftahudinRini HasibuanTatik ChikmawatiMBI & UNS Soloarticleantioxidant, mda, selaginella, sodBiology (General)QH301-705.5ENBiodiversitas, Vol 20, Iss 12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	antioxidant, mda, selaginella, sod Biology (General) QH301-705.5
spellingShingle	antioxidant, mda, selaginella, sod Biology (General) QH301-705.5 M Miftahudin Rini Hasibuan Tatik Chikmawati Antioxidant activity of ethanolic extract of three Selaginella species from Java Island, Indonesia
description	Abstract. Miftahudin, Hasibuan RS, Chikmawati T. 2019. Antioxidant activity of ethanolic extract of three Selaginella species from Java Island, Indonesia. Biodiversitas 20: 3715-3722. Three Selaginella species, S. ornata, S. plana, and S. willdenowii, from Java Island, Indonesia, have been known to have antioxidant properties; however, in vivo antioxidant activities of these species have not been reported. This research aimed to evaluate the in vivo antioxidant activity of ethanolic extract of three Selaginella species. The 70% ethanol extract of three Selaginella species at four different doses was administered to mice one day before being treated with oxidative stress. The liver tissue of mice treated with or without oxidative stress was analyzed their lipid peroxidation by measuring MDA concentration and Superoxide Dismutase (SOD) activities. The results showed that there were variations in antioxidant activity among the three Selaginella species. In general, the dose of 0.3 g extract kg-1 BW has been able to reduce lipid peroxidation and increase SOD activity. The administration of S. ornata extract to the mice at 1.2 g extract kg-1 BW reduced the MDA concentration to the lowest level, but the same dose of two other Selaginella extracts caused toxic effects in mice. The antioxidant activities of S. ornata and S. plana were better than that of S. willdenowii extract, and among those species, S. ornata has the best antioxidant activity.
format	article
author	M Miftahudin Rini Hasibuan Tatik Chikmawati
author_facet	M Miftahudin Rini Hasibuan Tatik Chikmawati
author_sort	M Miftahudin
title	Antioxidant activity of ethanolic extract of three Selaginella species from Java Island, Indonesia
title_short	Antioxidant activity of ethanolic extract of three Selaginella species from Java Island, Indonesia
title_full	Antioxidant activity of ethanolic extract of three Selaginella species from Java Island, Indonesia
title_fullStr	Antioxidant activity of ethanolic extract of three Selaginella species from Java Island, Indonesia
title_full_unstemmed	Antioxidant activity of ethanolic extract of three Selaginella species from Java Island, Indonesia
title_sort	antioxidant activity of ethanolic extract of three selaginella species from java island, indonesia
publisher	MBI & UNS Solo
publishDate	2019
url	https://doaj.org/article/daabc79eca794477ba9da0b0f290fece
work_keys_str_mv	AT mmiftahudin antioxidantactivityofethanolicextractofthreeselaginellaspeciesfromjavaislandindonesia AT rinihasibuan antioxidantactivityofethanolicextractofthreeselaginellaspeciesfromjavaislandindonesia AT tatikchikmawati antioxidantactivityofethanolicextractofthreeselaginellaspeciesfromjavaislandindonesia
_version_	1718418612524417024

Antioxidant activity of ethanolic extract of three Selaginella species from Java Island, Indonesia

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