Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin

Heterochromatin protein 1 (HP1), including HP1 α, β and γ, is a family of non-histone chromatin factors thought to be involved in chromatin organization. Here, the authors show that dimeric HP1β interacts dynamically with H3K9me3, a hallmark of heterochromatin, and bridges condensed chromatin.

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Autores principales:	Kyoko Hiragami-Hamada, Szabolcs Soeroes, Miroslav Nikolov, Bryan Wilkins, Sarah Kreuz, Carol Chen, Inti A. De La Rosa-Velázquez, Hans Michael Zenn, Nils Kost, Wiebke Pohl, Aleksandar Chernev, Dirk Schwarzer, Thomas Jenuwein, Matthew Lorincz, Bastian Zimmermann, Peter Jomo Walla, Heinz Neumann, Tuncay Baubec, Henning Urlaub, Wolfgang Fischle
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/daad9f601a9746829955629c5cc1bf39
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spelling	oai:doaj.org-article:daad9f601a9746829955629c5cc1bf392021-12-02T14:38:34ZDynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin10.1038/ncomms113102041-1723https://doaj.org/article/daad9f601a9746829955629c5cc1bf392016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11310https://doaj.org/toc/2041-1723Heterochromatin protein 1 (HP1), including HP1 α, β and γ, is a family of non-histone chromatin factors thought to be involved in chromatin organization. Here, the authors show that dimeric HP1β interacts dynamically with H3K9me3, a hallmark of heterochromatin, and bridges condensed chromatin.Kyoko Hiragami-HamadaSzabolcs SoeroesMiroslav NikolovBryan WilkinsSarah KreuzCarol ChenInti A. De La Rosa-VelázquezHans Michael ZennNils KostWiebke PohlAleksandar ChernevDirk SchwarzerThomas JenuweinMatthew LorinczBastian ZimmermannPeter Jomo WallaHeinz NeumannTuncay BaubecHenning UrlaubWolfgang FischleNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kyoko Hiragami-Hamada Szabolcs Soeroes Miroslav Nikolov Bryan Wilkins Sarah Kreuz Carol Chen Inti A. De La Rosa-Velázquez Hans Michael Zenn Nils Kost Wiebke Pohl Aleksandar Chernev Dirk Schwarzer Thomas Jenuwein Matthew Lorincz Bastian Zimmermann Peter Jomo Walla Heinz Neumann Tuncay Baubec Henning Urlaub Wolfgang Fischle Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin
description	Heterochromatin protein 1 (HP1), including HP1 α, β and γ, is a family of non-histone chromatin factors thought to be involved in chromatin organization. Here, the authors show that dimeric HP1β interacts dynamically with H3K9me3, a hallmark of heterochromatin, and bridges condensed chromatin.
format	article
author	Kyoko Hiragami-Hamada Szabolcs Soeroes Miroslav Nikolov Bryan Wilkins Sarah Kreuz Carol Chen Inti A. De La Rosa-Velázquez Hans Michael Zenn Nils Kost Wiebke Pohl Aleksandar Chernev Dirk Schwarzer Thomas Jenuwein Matthew Lorincz Bastian Zimmermann Peter Jomo Walla Heinz Neumann Tuncay Baubec Henning Urlaub Wolfgang Fischle
author_facet	Kyoko Hiragami-Hamada Szabolcs Soeroes Miroslav Nikolov Bryan Wilkins Sarah Kreuz Carol Chen Inti A. De La Rosa-Velázquez Hans Michael Zenn Nils Kost Wiebke Pohl Aleksandar Chernev Dirk Schwarzer Thomas Jenuwein Matthew Lorincz Bastian Zimmermann Peter Jomo Walla Heinz Neumann Tuncay Baubec Henning Urlaub Wolfgang Fischle
author_sort	Kyoko Hiragami-Hamada
title	Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin
title_short	Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin
title_full	Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin
title_fullStr	Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin
title_full_unstemmed	Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin
title_sort	dynamic and flexible h3k9me3 bridging via hp1β dimerization establishes a plastic state of condensed chromatin
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/daad9f601a9746829955629c5cc1bf39
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Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin

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