Mechanisms and consequences of casein kinase II and ankyrin-3 regulation of the epithelial Na+ channel

Mechanisms and consequences of casein kinase II and ankyrin-3 regulation of the epithelial Na+ channel

Abstract Activity of the Epithelial Na+ Channel (ENaC) in the distal nephron fine-tunes renal sodium excretion. Appropriate sodium excretion is a key factor in the regulation of blood pressure. Consequently, abnormalities in ENaC function can cause hypertension. Casein Kinase II (CKII) phosphorylate...

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Autores principales: Tarek Mohamed Abd El-Aziz, Antonio G. Soares, Elena Mironova, Nina Boiko, Amanpreet Kaur, Crystal R. Archer, James D. Stockand, Jonathan M. Berman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/dab1b85344ad40b297a5b5d8718ba07c
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