Innovative motor and cognitive dual-task approaches combining upper and lower limbs may improve dementia early detection

Abstract Motor and Cognitive Dual-Task (MCDT) represents an innovative chance to assess Mild Cognitive Impairment (MCI). We compare two novel MCDTs, fore-finger tapping (FTAP), toe-tapping (TTHP), to gold standards for cognitive screening (Mini-Mental State Examination—MMSE), and to a well-establish...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Gianmaria Mancioppi, Laura Fiorini, Erika Rovini, Radia Zeghari, Auriane Gros, Valeria Manera, Philippe Robert, Filippo Cavallo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/dab27945648b4d9c8a710d3d04ab2b54
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:dab27945648b4d9c8a710d3d04ab2b54
record_format	dspace
spelling	oai:doaj.org-article:dab27945648b4d9c8a710d3d04ab2b542021-12-02T13:26:37ZInnovative motor and cognitive dual-task approaches combining upper and lower limbs may improve dementia early detection10.1038/s41598-021-86579-32045-2322https://doaj.org/article/dab27945648b4d9c8a710d3d04ab2b542021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-86579-3https://doaj.org/toc/2045-2322Abstract Motor and Cognitive Dual-Task (MCDT) represents an innovative chance to assess Mild Cognitive Impairment (MCI). We compare two novel MCDTs, fore-finger tapping (FTAP), toe-tapping (TTHP), to gold standards for cognitive screening (Mini-Mental State Examination—MMSE), and to a well-established MCDT (GAIT). We administered the aforementioned MCDTs to 44 subjects (MCIs and controls). Motor parameters were extracted, and correlations with MMSE investigated. Logistic regression models were built, and AUC areas computed. Spearman’s correlation demonstrated that FTAP and TTHP significantly correlate with MMSE, at each cognitive load. AUC areas computed report similar (FTAP, 0.87), and even higher (TTHP, 0.97) capability to identify MCIs, if compared to GAIT (0.92). We investigated the use of novel MCDT approaches to assess MCI, aiming to enrich the clinical repertoire with objective and non-invasive tools. Our protocol shows good correlations with MMSE, and reaches high performances in identifying MCI, adopting simpler exercises.Gianmaria MancioppiLaura FioriniErika RoviniRadia ZeghariAuriane GrosValeria ManeraPhilippe RobertFilippo CavalloNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Gianmaria Mancioppi Laura Fiorini Erika Rovini Radia Zeghari Auriane Gros Valeria Manera Philippe Robert Filippo Cavallo Innovative motor and cognitive dual-task approaches combining upper and lower limbs may improve dementia early detection
description	Abstract Motor and Cognitive Dual-Task (MCDT) represents an innovative chance to assess Mild Cognitive Impairment (MCI). We compare two novel MCDTs, fore-finger tapping (FTAP), toe-tapping (TTHP), to gold standards for cognitive screening (Mini-Mental State Examination—MMSE), and to a well-established MCDT (GAIT). We administered the aforementioned MCDTs to 44 subjects (MCIs and controls). Motor parameters were extracted, and correlations with MMSE investigated. Logistic regression models were built, and AUC areas computed. Spearman’s correlation demonstrated that FTAP and TTHP significantly correlate with MMSE, at each cognitive load. AUC areas computed report similar (FTAP, 0.87), and even higher (TTHP, 0.97) capability to identify MCIs, if compared to GAIT (0.92). We investigated the use of novel MCDT approaches to assess MCI, aiming to enrich the clinical repertoire with objective and non-invasive tools. Our protocol shows good correlations with MMSE, and reaches high performances in identifying MCI, adopting simpler exercises.
format	article
author	Gianmaria Mancioppi Laura Fiorini Erika Rovini Radia Zeghari Auriane Gros Valeria Manera Philippe Robert Filippo Cavallo
author_facet	Gianmaria Mancioppi Laura Fiorini Erika Rovini Radia Zeghari Auriane Gros Valeria Manera Philippe Robert Filippo Cavallo
author_sort	Gianmaria Mancioppi
title	Innovative motor and cognitive dual-task approaches combining upper and lower limbs may improve dementia early detection
title_short	Innovative motor and cognitive dual-task approaches combining upper and lower limbs may improve dementia early detection
title_full	Innovative motor and cognitive dual-task approaches combining upper and lower limbs may improve dementia early detection
title_fullStr	Innovative motor and cognitive dual-task approaches combining upper and lower limbs may improve dementia early detection
title_full_unstemmed	Innovative motor and cognitive dual-task approaches combining upper and lower limbs may improve dementia early detection
title_sort	innovative motor and cognitive dual-task approaches combining upper and lower limbs may improve dementia early detection
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/dab27945648b4d9c8a710d3d04ab2b54
work_keys_str_mv	AT gianmariamancioppi innovativemotorandcognitivedualtaskapproachescombiningupperandlowerlimbsmayimprovedementiaearlydetection AT laurafiorini innovativemotorandcognitivedualtaskapproachescombiningupperandlowerlimbsmayimprovedementiaearlydetection AT erikarovini innovativemotorandcognitivedualtaskapproachescombiningupperandlowerlimbsmayimprovedementiaearlydetection AT radiazeghari innovativemotorandcognitivedualtaskapproachescombiningupperandlowerlimbsmayimprovedementiaearlydetection AT aurianegros innovativemotorandcognitivedualtaskapproachescombiningupperandlowerlimbsmayimprovedementiaearlydetection AT valeriamanera innovativemotorandcognitivedualtaskapproachescombiningupperandlowerlimbsmayimprovedementiaearlydetection AT philipperobert innovativemotorandcognitivedualtaskapproachescombiningupperandlowerlimbsmayimprovedementiaearlydetection AT filippocavallo innovativemotorandcognitivedualtaskapproachescombiningupperandlowerlimbsmayimprovedementiaearlydetection
_version_	1718393063261339648

Innovative motor and cognitive dual-task approaches combining upper and lower limbs may improve dementia early detection

Ejemplares similares