Fully automatic liver segmentation combining multi-dimensional graph cut with shape information in 3D CT images

Abstract Liver segmentation is an essential procedure in computer-assisted surgery, radiotherapy, and volume measurement. It is still a challenging task to extract liver tissue from 3D CT images owing to nearby organs with similar intensities. In this paper, an automatic approach integrating multi-d...

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Autores principales: Xuesong Lu, Qinlan Xie, Yunfei Zha, Defeng Wang
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Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/dab462a1c5404c81a853b6e1c93605f0
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spelling oai:doaj.org-article:dab462a1c5404c81a853b6e1c93605f02021-12-02T16:08:25ZFully automatic liver segmentation combining multi-dimensional graph cut with shape information in 3D CT images10.1038/s41598-018-28787-y2045-2322https://doaj.org/article/dab462a1c5404c81a853b6e1c93605f02018-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-28787-yhttps://doaj.org/toc/2045-2322Abstract Liver segmentation is an essential procedure in computer-assisted surgery, radiotherapy, and volume measurement. It is still a challenging task to extract liver tissue from 3D CT images owing to nearby organs with similar intensities. In this paper, an automatic approach integrating multi-dimensional features into graph cut refinement is developed and validated. Multi-atlas segmentation is utilized to estimate the coarse shape of liver on the target image. The unsigned distance field based on initial shape is then calculated throughout the whole image, which aims at automatic graph construction during refinement procedure. Finally, multi-dimensional features and shape constraints are embedded into graph cut framework. The optimal liver region can be precisely detected with a minimal cost. The proposed technique is evaluated on 40 CT scans, obtained from two public databases Sliver07 and 3Dircadb1. The dataset Sliver07 is considered as the training set for parameter learning. On the dataset 3Dircadb1, the average of volume overlap is up to 94%. The experiment results indicate that the proposed method has ability to reach the desired boundary of liver and has potential value for clinical application.Xuesong LuQinlan XieYunfei ZhaDefeng WangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Xuesong Lu
Qinlan Xie
Yunfei Zha
Defeng Wang
Fully automatic liver segmentation combining multi-dimensional graph cut with shape information in 3D CT images
description Abstract Liver segmentation is an essential procedure in computer-assisted surgery, radiotherapy, and volume measurement. It is still a challenging task to extract liver tissue from 3D CT images owing to nearby organs with similar intensities. In this paper, an automatic approach integrating multi-dimensional features into graph cut refinement is developed and validated. Multi-atlas segmentation is utilized to estimate the coarse shape of liver on the target image. The unsigned distance field based on initial shape is then calculated throughout the whole image, which aims at automatic graph construction during refinement procedure. Finally, multi-dimensional features and shape constraints are embedded into graph cut framework. The optimal liver region can be precisely detected with a minimal cost. The proposed technique is evaluated on 40 CT scans, obtained from two public databases Sliver07 and 3Dircadb1. The dataset Sliver07 is considered as the training set for parameter learning. On the dataset 3Dircadb1, the average of volume overlap is up to 94%. The experiment results indicate that the proposed method has ability to reach the desired boundary of liver and has potential value for clinical application.
format article
author Xuesong Lu
Qinlan Xie
Yunfei Zha
Defeng Wang
author_facet Xuesong Lu
Qinlan Xie
Yunfei Zha
Defeng Wang
author_sort Xuesong Lu
title Fully automatic liver segmentation combining multi-dimensional graph cut with shape information in 3D CT images
title_short Fully automatic liver segmentation combining multi-dimensional graph cut with shape information in 3D CT images
title_full Fully automatic liver segmentation combining multi-dimensional graph cut with shape information in 3D CT images
title_fullStr Fully automatic liver segmentation combining multi-dimensional graph cut with shape information in 3D CT images
title_full_unstemmed Fully automatic liver segmentation combining multi-dimensional graph cut with shape information in 3D CT images
title_sort fully automatic liver segmentation combining multi-dimensional graph cut with shape information in 3d ct images
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/dab462a1c5404c81a853b6e1c93605f0
work_keys_str_mv AT xuesonglu fullyautomaticliversegmentationcombiningmultidimensionalgraphcutwithshapeinformationin3dctimages
AT qinlanxie fullyautomaticliversegmentationcombiningmultidimensionalgraphcutwithshapeinformationin3dctimages
AT yunfeizha fullyautomaticliversegmentationcombiningmultidimensionalgraphcutwithshapeinformationin3dctimages
AT defengwang fullyautomaticliversegmentationcombiningmultidimensionalgraphcutwithshapeinformationin3dctimages
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