Sphingolipid-dependent Dscam sorting regulates axon segregation

Sphingolipid-dependent Dscam sorting regulates axon segregation

Little is known about the initial segregation of axonal and dendritic proteins during the differentiation of newly generated neurons. Here authors use a forward genetic screen to identify the role of sphingolipids in regulating the sub-cellular distribution of Dscam for neuronal patterning in Drosop...

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Autores principales: Gaurav Goyal, Junfeng Zheng, Elisabeth Adam, Georg Steffes, Mamta Jain, Kristaps Klavins, Thomas Hummel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/dac65b4ee54f4d37850c41772c6a9f87
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spelling oai:doaj.org-article:dac65b4ee54f4d37850c41772c6a9f872021-12-02T14:39:57ZSphingolipid-dependent Dscam sorting regulates axon segregation10.1038/s41467-019-08765-22041-1723https://doaj.org/article/dac65b4ee54f4d37850c41772c6a9f872019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08765-2https://doaj.org/toc/2041-1723Little is known about the initial segregation of axonal and dendritic proteins during the differentiation of newly generated neurons. Here authors use a forward genetic screen to identify the role of sphingolipids in regulating the sub-cellular distribution of Dscam for neuronal patterning in Drosophila Mushroom BodiesGaurav GoyalJunfeng ZhengElisabeth AdamGeorg SteffesMamta JainKristaps KlavinsThomas HummelNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gaurav Goyal
Junfeng Zheng
Elisabeth Adam
Georg Steffes
Mamta Jain
Kristaps Klavins
Thomas Hummel
Sphingolipid-dependent Dscam sorting regulates axon segregation
description Little is known about the initial segregation of axonal and dendritic proteins during the differentiation of newly generated neurons. Here authors use a forward genetic screen to identify the role of sphingolipids in regulating the sub-cellular distribution of Dscam for neuronal patterning in Drosophila Mushroom Bodies
format article
author Gaurav Goyal
Junfeng Zheng
Elisabeth Adam
Georg Steffes
Mamta Jain
Kristaps Klavins
Thomas Hummel
author_facet Gaurav Goyal
Junfeng Zheng
Elisabeth Adam
Georg Steffes
Mamta Jain
Kristaps Klavins
Thomas Hummel
author_sort Gaurav Goyal
title Sphingolipid-dependent Dscam sorting regulates axon segregation
title_short Sphingolipid-dependent Dscam sorting regulates axon segregation
title_full Sphingolipid-dependent Dscam sorting regulates axon segregation
title_fullStr Sphingolipid-dependent Dscam sorting regulates axon segregation
title_full_unstemmed Sphingolipid-dependent Dscam sorting regulates axon segregation
title_sort sphingolipid-dependent dscam sorting regulates axon segregation
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/dac65b4ee54f4d37850c41772c6a9f87
work_keys_str_mv AT gauravgoyal sphingolipiddependentdscamsortingregulatesaxonsegregation
AT junfengzheng sphingolipiddependentdscamsortingregulatesaxonsegregation
AT elisabethadam sphingolipiddependentdscamsortingregulatesaxonsegregation
AT georgsteffes sphingolipiddependentdscamsortingregulatesaxonsegregation
AT mamtajain sphingolipiddependentdscamsortingregulatesaxonsegregation
AT kristapsklavins sphingolipiddependentdscamsortingregulatesaxonsegregation
AT thomashummel sphingolipiddependentdscamsortingregulatesaxonsegregation
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