Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses

Antigen presentation is generally considered the domain of innate immune cells, but CD4+ T cells can transphagocytose bacteria from infected dendritic cells. Here the authors show CD4+ T cells can transphagocytose bacterial and tumour antigens and present them to CD8+ T cells to activate memory and...

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Autores principales:	Aránzazu Cruz-Adalia, Guillermo Ramirez-Santiago, Jesús Osuna-Pérez, Mónica Torres-Torresano, Virgina Zorita, Ana Martínez-Riaño, Viola Boccasavia, Aldo Borroto, Gloria Martínez del Hoyo, José María González-Granado, Balbino Alarcón, Francisco Sánchez-Madrid, Esteban Veiga
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/dad437495b54437c9d5f650b07fe1bc5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:dad437495b54437c9d5f650b07fe1bc52021-12-02T14:42:21ZConventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses10.1038/s41467-017-01661-72041-1723https://doaj.org/article/dad437495b54437c9d5f650b07fe1bc52017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01661-7https://doaj.org/toc/2041-1723Antigen presentation is generally considered the domain of innate immune cells, but CD4+ T cells can transphagocytose bacteria from infected dendritic cells. Here the authors show CD4+ T cells can transphagocytose bacterial and tumour antigens and present them to CD8+ T cells to activate memory and cytotoxic functions.Aránzazu Cruz-AdaliaGuillermo Ramirez-SantiagoJesús Osuna-PérezMónica Torres-TorresanoVirgina ZoritaAna Martínez-RiañoViola BoccasaviaAldo BorrotoGloria Martínez del HoyoJosé María González-GranadoBalbino AlarcónFrancisco Sánchez-MadridEsteban VeigaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Aránzazu Cruz-Adalia Guillermo Ramirez-Santiago Jesús Osuna-Pérez Mónica Torres-Torresano Virgina Zorita Ana Martínez-Riaño Viola Boccasavia Aldo Borroto Gloria Martínez del Hoyo José María González-Granado Balbino Alarcón Francisco Sánchez-Madrid Esteban Veiga Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses
description	Antigen presentation is generally considered the domain of innate immune cells, but CD4+ T cells can transphagocytose bacteria from infected dendritic cells. Here the authors show CD4+ T cells can transphagocytose bacterial and tumour antigens and present them to CD8+ T cells to activate memory and cytotoxic functions.
format	article
author	Aránzazu Cruz-Adalia Guillermo Ramirez-Santiago Jesús Osuna-Pérez Mónica Torres-Torresano Virgina Zorita Ana Martínez-Riaño Viola Boccasavia Aldo Borroto Gloria Martínez del Hoyo José María González-Granado Balbino Alarcón Francisco Sánchez-Madrid Esteban Veiga
author_facet	Aránzazu Cruz-Adalia Guillermo Ramirez-Santiago Jesús Osuna-Pérez Mónica Torres-Torresano Virgina Zorita Ana Martínez-Riaño Viola Boccasavia Aldo Borroto Gloria Martínez del Hoyo José María González-Granado Balbino Alarcón Francisco Sánchez-Madrid Esteban Veiga
author_sort	Aránzazu Cruz-Adalia
title	Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses
title_short	Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses
title_full	Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses
title_fullStr	Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses
title_full_unstemmed	Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses
title_sort	conventional cd4+ t cells present bacterial antigens to induce cytotoxic and memory cd8+ t cell responses
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/dad437495b54437c9d5f650b07fe1bc5
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Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses

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