Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses
Antigen presentation is generally considered the domain of innate immune cells, but CD4+ T cells can transphagocytose bacteria from infected dendritic cells. Here the authors show CD4+ T cells can transphagocytose bacterial and tumour antigens and present them to CD8+ T cells to activate memory and...
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Autores principales: | Aránzazu Cruz-Adalia, Guillermo Ramirez-Santiago, Jesús Osuna-Pérez, Mónica Torres-Torresano, Virgina Zorita, Ana Martínez-Riaño, Viola Boccasavia, Aldo Borroto, Gloria Martínez del Hoyo, José María González-Granado, Balbino Alarcón, Francisco Sánchez-Madrid, Esteban Veiga |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/dad437495b54437c9d5f650b07fe1bc5 |
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