Improved prediction of smoking status via isoform-aware RNA-seq deep learning models.

Most predictive models based on gene expression data do not leverage information related to gene splicing, despite the fact that splicing is a fundamental feature of eukaryotic gene expression. Cigarette smoking is an important environmental risk factor for many diseases, and it has profound effects...

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Autores principales: Zifeng Wang, Aria Masoomi, Zhonghui Xu, Adel Boueiz, Sool Lee, Tingting Zhao, Russell Bowler, Michael Cho, Edwin K Silverman, Craig Hersh, Jennifer Dy, Peter J Castaldi
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/dad7f97d944747acba04531e3bfd1c45
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