ADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals

D7 proteins are highly abundant in the salivary glands of several blood feeding insects. Here, the authors study the ligand binding specificity and physiological roles of the mosquito D7 proteins CxD7L1 and CxD7L2, showing that CxD7L1 acquired ADP-binding properties to enhance blood feeding in mamma...

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Autores principales:	Ines Martin-Martin, Andrew Paige, Paola Carolina Valenzuela Leon, Apostolos G. Gittis, Olivia Kern, Brian Bonilla, Andrezza Campos Chagas, Sundar Ganesan, Leticia Barion Smith, David N. Garboczi, Eric Calvo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/dada7b2dad22487ba29eabdf46abee8b
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spelling	oai:doaj.org-article:dada7b2dad22487ba29eabdf46abee8b2021-12-02T17:30:39ZADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals10.1038/s41467-020-16665-z2041-1723https://doaj.org/article/dada7b2dad22487ba29eabdf46abee8b2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16665-zhttps://doaj.org/toc/2041-1723D7 proteins are highly abundant in the salivary glands of several blood feeding insects. Here, the authors study the ligand binding specificity and physiological roles of the mosquito D7 proteins CxD7L1 and CxD7L2, showing that CxD7L1 acquired ADP-binding properties to enhance blood feeding in mammals.Ines Martin-MartinAndrew PaigePaola Carolina Valenzuela LeonApostolos G. GittisOlivia KernBrian BonillaAndrezza Campos ChagasSundar GanesanLeticia Barion SmithDavid N. GarbocziEric CalvoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ines Martin-Martin Andrew Paige Paola Carolina Valenzuela Leon Apostolos G. Gittis Olivia Kern Brian Bonilla Andrezza Campos Chagas Sundar Ganesan Leticia Barion Smith David N. Garboczi Eric Calvo ADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals
description	D7 proteins are highly abundant in the salivary glands of several blood feeding insects. Here, the authors study the ligand binding specificity and physiological roles of the mosquito D7 proteins CxD7L1 and CxD7L2, showing that CxD7L1 acquired ADP-binding properties to enhance blood feeding in mammals.
format	article
author	Ines Martin-Martin Andrew Paige Paola Carolina Valenzuela Leon Apostolos G. Gittis Olivia Kern Brian Bonilla Andrezza Campos Chagas Sundar Ganesan Leticia Barion Smith David N. Garboczi Eric Calvo
author_facet	Ines Martin-Martin Andrew Paige Paola Carolina Valenzuela Leon Apostolos G. Gittis Olivia Kern Brian Bonilla Andrezza Campos Chagas Sundar Ganesan Leticia Barion Smith David N. Garboczi Eric Calvo
author_sort	Ines Martin-Martin
title	ADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals
title_short	ADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals
title_full	ADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals
title_fullStr	ADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals
title_full_unstemmed	ADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals
title_sort	adp binding by the culex quinquefasciatus mosquito d7 salivary protein enhances blood feeding on mammals
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/dada7b2dad22487ba29eabdf46abee8b
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ADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals

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