The concerted roles of FANCM and Rad52 in the protection of common fragile sites

Fanconi anemia core proteins have been linked to common fragile site stability. Here the authors shed light into the role of FANCM in common fragile site protection by suppressing double-strand break formation and mitotic recombination.

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Detalles Bibliográficos
Autores principales: Hailong Wang, Shibo Li, Joshua Oaks, Jianping Ren, Lei Li, Xiaohua Wu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/dae41633be9c45748b806ba0419f6c58
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Descripción
Sumario:Fanconi anemia core proteins have been linked to common fragile site stability. Here the authors shed light into the role of FANCM in common fragile site protection by suppressing double-strand break formation and mitotic recombination.