EBI2 is a negative regulator of type I interferons in plasmacytoid and myeloid dendritic cells.

EBI2 is a negative regulator of type I interferons in plasmacytoid and myeloid dendritic cells.

Epstein-Barr virus induced receptor 2 (EBI2), a Gαi-coupled G protein-coupled receptor, is a chemotactic receptor for B, T and dendritic cells (DC). Genetic studies have also implicated EBI2 as a regulator of an interferon regulatory factor 7 (IRF7)-driven inflammatory network (IDIN) associated with...

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Autores principales: Eugene Y Chiang, Robert J Johnston, Jane L Grogan
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/dae4ec9125314ff48442f1cf9a32929c
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