Next generation Fc scaffold for multispecific antibodies

Next generation Fc scaffold for multispecific antibodies

Summary: Bispecific antibodies (Bispecifics) demonstrate exceptional clinical potential to address some of the most complex diseases. However, Bispecific production in a single cell often requires the correct pairing of multiple polypeptide chains for desired assembly. This is a considerable hurdle...

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Bibliographic Details
Main Authors: Bram Estes, Athena Sudom, Danyang Gong, Douglas A. Whittington, Vivian Li, Christopher Mohr, Danqing Li, Timothy P. Riley, Stone D.-H. Shi, Jun Zhang, Fernando Garces, Zhulun Wang
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Biochemistry
Bioengineering
Biomolecular engineering
Structural biology
Science
Q
Online Access:https://doaj.org/article/daec344ee874422b8d613ca7fb390ad7
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https://doaj.org/article/daec344ee874422b8d613ca7fb390ad7

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