Bis(zinc(II)-dipicolylamine)-functionalized sub-2 μm core-shell microspheres for the analysis of N-phosphoproteome

N-phosphorylation plays a critical role in central metabolism and signaling processes, however, enrichment methods for N-phosphopeptides are limited by the P-N bond lability. Here, the authors report the synthesis and use of silica microspheres functionalized with bis(zinc(II)-dipicolylamine) in N-p...

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Autores principales:	Yechen Hu, Bo Jiang, Yejing Weng, Zhigang Sui, Baofeng Zhao, Yuanbo Chen, Lukuan Liu, Qiong Wu, Zhen Liang, Lihua Zhang, Yukui Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/dafbb736085f4e9b9a0789109c8e7bb8
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spelling	oai:doaj.org-article:dafbb736085f4e9b9a0789109c8e7bb82021-12-02T14:40:53ZBis(zinc(II)-dipicolylamine)-functionalized sub-2 μm core-shell microspheres for the analysis of N-phosphoproteome10.1038/s41467-020-20026-12041-1723https://doaj.org/article/dafbb736085f4e9b9a0789109c8e7bb82020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20026-1https://doaj.org/toc/2041-1723N-phosphorylation plays a critical role in central metabolism and signaling processes, however, enrichment methods for N-phosphopeptides are limited by the P-N bond lability. Here, the authors report the synthesis and use of silica microspheres functionalized with bis(zinc(II)-dipicolylamine) in N-phosphopeptides effective enrichment.Yechen HuBo JiangYejing WengZhigang SuiBaofeng ZhaoYuanbo ChenLukuan LiuQiong WuZhen LiangLihua ZhangYukui ZhangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yechen Hu Bo Jiang Yejing Weng Zhigang Sui Baofeng Zhao Yuanbo Chen Lukuan Liu Qiong Wu Zhen Liang Lihua Zhang Yukui Zhang Bis(zinc(II)-dipicolylamine)-functionalized sub-2 μm core-shell microspheres for the analysis of N-phosphoproteome
description	N-phosphorylation plays a critical role in central metabolism and signaling processes, however, enrichment methods for N-phosphopeptides are limited by the P-N bond lability. Here, the authors report the synthesis and use of silica microspheres functionalized with bis(zinc(II)-dipicolylamine) in N-phosphopeptides effective enrichment.
format	article
author	Yechen Hu Bo Jiang Yejing Weng Zhigang Sui Baofeng Zhao Yuanbo Chen Lukuan Liu Qiong Wu Zhen Liang Lihua Zhang Yukui Zhang
author_facet	Yechen Hu Bo Jiang Yejing Weng Zhigang Sui Baofeng Zhao Yuanbo Chen Lukuan Liu Qiong Wu Zhen Liang Lihua Zhang Yukui Zhang
author_sort	Yechen Hu
title	Bis(zinc(II)-dipicolylamine)-functionalized sub-2 μm core-shell microspheres for the analysis of N-phosphoproteome
title_short	Bis(zinc(II)-dipicolylamine)-functionalized sub-2 μm core-shell microspheres for the analysis of N-phosphoproteome
title_full	Bis(zinc(II)-dipicolylamine)-functionalized sub-2 μm core-shell microspheres for the analysis of N-phosphoproteome
title_fullStr	Bis(zinc(II)-dipicolylamine)-functionalized sub-2 μm core-shell microspheres for the analysis of N-phosphoproteome
title_full_unstemmed	Bis(zinc(II)-dipicolylamine)-functionalized sub-2 μm core-shell microspheres for the analysis of N-phosphoproteome
title_sort	bis(zinc(ii)-dipicolylamine)-functionalized sub-2 μm core-shell microspheres for the analysis of n-phosphoproteome
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/dafbb736085f4e9b9a0789109c8e7bb8
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Bis(zinc(II)-dipicolylamine)-functionalized sub-2 μm core-shell microspheres for the analysis of N-phosphoproteome

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