Modeling spinal muscular atrophy in Drosophila.

Modeling spinal muscular atrophy in Drosophila.

Spinal Muscular Atrophy (SMA), a recessive hereditary neurodegenerative disease in humans, has been linked to mutations in the survival motor neuron (SMN) gene. SMA patients display early onset lethality coupled with motor neuron loss and skeletal muscle atrophy. We used Drosophila, which encodes a...

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Bibliographic Details
Main Authors: Howard Chia-Hao Chang, Douglas N Dimlich, Takakazu Yokokura, Ashim Mukherjee, Mark W Kankel, Anindya Sen, Vasanthi Sridhar, Tudor A Fulga, Anne C Hart, David Van Vactor, Spyros Artavanis-Tsakonas
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2008
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/dafc3ca54a234f99bc04d8a718fc5c1a
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