The MRX complex plays multiple functions in resection of Yku- and Rif2-protected DNA ends.
The ends of both double-strand breaks (DSBs) and telomeres undergo tightly regulated 5' to 3' resection. Resection of DNA ends, which is specifically inhibited during the G1 cell cycle phase, requires the MRX complex, Sae2, Sgs1 and Exo1. Moreover, it is negatively regulated by the non-hom...
Guardado en:
Autores principales: | Diego Bonetti, Michela Clerici, Nicola Manfrini, Giovanna Lucchini, Maria Pia Longhese |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/db0027d7be4c4230a880f2385becbc25 |
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