Dense and accurate whole-chromosome haplotyping of individual genomes

Haplotype information is important in investigating many biological phenomena. Here, Porubsky et al. combine Strand-seq with long-read or linked-read sequencing to obtain complete and genome-wide haplotypes of a single individual genome at manageable costs.

Guardado en:

Detalles Bibliográficos
Autores principales:	David Porubsky, Shilpa Garg, Ashley D. Sanders, Jan O. Korbel, Victor Guryev, Peter M. Lansdorp, Tobias Marschall
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/db0127d509434bd2b9aa41d8de8838bc
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:db0127d509434bd2b9aa41d8de8838bc
record_format	dspace
spelling	oai:doaj.org-article:db0127d509434bd2b9aa41d8de8838bc2021-12-02T15:38:56ZDense and accurate whole-chromosome haplotyping of individual genomes10.1038/s41467-017-01389-42041-1723https://doaj.org/article/db0127d509434bd2b9aa41d8de8838bc2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01389-4https://doaj.org/toc/2041-1723Haplotype information is important in investigating many biological phenomena. Here, Porubsky et al. combine Strand-seq with long-read or linked-read sequencing to obtain complete and genome-wide haplotypes of a single individual genome at manageable costs.David PorubskyShilpa GargAshley D. SandersJan O. KorbelVictor GuryevPeter M. LansdorpTobias MarschallNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q David Porubsky Shilpa Garg Ashley D. Sanders Jan O. Korbel Victor Guryev Peter M. Lansdorp Tobias Marschall Dense and accurate whole-chromosome haplotyping of individual genomes
description	Haplotype information is important in investigating many biological phenomena. Here, Porubsky et al. combine Strand-seq with long-read or linked-read sequencing to obtain complete and genome-wide haplotypes of a single individual genome at manageable costs.
format	article
author	David Porubsky Shilpa Garg Ashley D. Sanders Jan O. Korbel Victor Guryev Peter M. Lansdorp Tobias Marschall
author_facet	David Porubsky Shilpa Garg Ashley D. Sanders Jan O. Korbel Victor Guryev Peter M. Lansdorp Tobias Marschall
author_sort	David Porubsky
title	Dense and accurate whole-chromosome haplotyping of individual genomes
title_short	Dense and accurate whole-chromosome haplotyping of individual genomes
title_full	Dense and accurate whole-chromosome haplotyping of individual genomes
title_fullStr	Dense and accurate whole-chromosome haplotyping of individual genomes
title_full_unstemmed	Dense and accurate whole-chromosome haplotyping of individual genomes
title_sort	dense and accurate whole-chromosome haplotyping of individual genomes
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/db0127d509434bd2b9aa41d8de8838bc
work_keys_str_mv	AT davidporubsky denseandaccuratewholechromosomehaplotypingofindividualgenomes AT shilpagarg denseandaccuratewholechromosomehaplotypingofindividualgenomes AT ashleydsanders denseandaccuratewholechromosomehaplotypingofindividualgenomes AT janokorbel denseandaccuratewholechromosomehaplotypingofindividualgenomes AT victorguryev denseandaccuratewholechromosomehaplotypingofindividualgenomes AT petermlansdorp denseandaccuratewholechromosomehaplotypingofindividualgenomes AT tobiasmarschall denseandaccuratewholechromosomehaplotypingofindividualgenomes
_version_	1718386078238375936

Dense and accurate whole-chromosome haplotyping of individual genomes

Ejemplares similares