Structure and dynamics of the drug-bound bacterial transporter EmrE in lipid bilayers
The small proton-coupled transporter EmrE confers multidrug resistance in bacteria. The structure of drug-bound EmrE in phospholipid bilayers is now determined using solid-state NMR. The structure provides detailed insights into the molecular mechanism of substrate recognition by this transporter.
Guardado en:
Autores principales: | Alexander A. Shcherbakov, Grant Hisao, Venkata S. Mandala, Nathan E. Thomas, Mohammad Soltani, E. A. Salter, James H. Davis, Katherine A. Henzler-Wildman, Mei Hong |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/db0829dbaea348d0bf08d38e1f44870d |
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