Silencing cortical activity during sound-localization training impairs auditory perceptual learning

Sensory circuits can adapt flexibly to changes in inputs yet the neural mechanisms related to experience dependent plasticity are not well understood. Here, the authors use optogenetic approaches in ferrets to show that suppression of auditory cortex during sound localization training can affect lea...

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Autores principales:	Victoria M. Bajo, Fernando R. Nodal, Clio Korn, Alexandra O. Constantinescu, Edward O. Mann, Edward S. Boyden, Andrew J. King
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/db0bc8f987054ce1bdf72aafba54aa74
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id	oai:doaj.org-article:db0bc8f987054ce1bdf72aafba54aa74
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spelling	oai:doaj.org-article:db0bc8f987054ce1bdf72aafba54aa742021-12-02T14:39:39ZSilencing cortical activity during sound-localization training impairs auditory perceptual learning10.1038/s41467-019-10770-42041-1723https://doaj.org/article/db0bc8f987054ce1bdf72aafba54aa742019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10770-4https://doaj.org/toc/2041-1723Sensory circuits can adapt flexibly to changes in inputs yet the neural mechanisms related to experience dependent plasticity are not well understood. Here, the authors use optogenetic approaches in ferrets to show that suppression of auditory cortex during sound localization training can affect learning.Victoria M. BajoFernando R. NodalClio KornAlexandra O. ConstantinescuEdward O. MannEdward S. BoydenAndrew J. KingNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Victoria M. Bajo Fernando R. Nodal Clio Korn Alexandra O. Constantinescu Edward O. Mann Edward S. Boyden Andrew J. King Silencing cortical activity during sound-localization training impairs auditory perceptual learning
description	Sensory circuits can adapt flexibly to changes in inputs yet the neural mechanisms related to experience dependent plasticity are not well understood. Here, the authors use optogenetic approaches in ferrets to show that suppression of auditory cortex during sound localization training can affect learning.
format	article
author	Victoria M. Bajo Fernando R. Nodal Clio Korn Alexandra O. Constantinescu Edward O. Mann Edward S. Boyden Andrew J. King
author_facet	Victoria M. Bajo Fernando R. Nodal Clio Korn Alexandra O. Constantinescu Edward O. Mann Edward S. Boyden Andrew J. King
author_sort	Victoria M. Bajo
title	Silencing cortical activity during sound-localization training impairs auditory perceptual learning
title_short	Silencing cortical activity during sound-localization training impairs auditory perceptual learning
title_full	Silencing cortical activity during sound-localization training impairs auditory perceptual learning
title_fullStr	Silencing cortical activity during sound-localization training impairs auditory perceptual learning
title_full_unstemmed	Silencing cortical activity during sound-localization training impairs auditory perceptual learning
title_sort	silencing cortical activity during sound-localization training impairs auditory perceptual learning
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/db0bc8f987054ce1bdf72aafba54aa74
work_keys_str_mv	AT victoriambajo silencingcorticalactivityduringsoundlocalizationtrainingimpairsauditoryperceptuallearning AT fernandornodal silencingcorticalactivityduringsoundlocalizationtrainingimpairsauditoryperceptuallearning AT cliokorn silencingcorticalactivityduringsoundlocalizationtrainingimpairsauditoryperceptuallearning AT alexandraoconstantinescu silencingcorticalactivityduringsoundlocalizationtrainingimpairsauditoryperceptuallearning AT edwardomann silencingcorticalactivityduringsoundlocalizationtrainingimpairsauditoryperceptuallearning AT edwardsboyden silencingcorticalactivityduringsoundlocalizationtrainingimpairsauditoryperceptuallearning AT andrewjking silencingcorticalactivityduringsoundlocalizationtrainingimpairsauditoryperceptuallearning
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Silencing cortical activity during sound-localization training impairs auditory perceptual learning

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