A deep learning-based model for screening and staging pneumoconiosis
Abstract This study aims to develop an artificial intelligence (AI)-based model to assist radiologists in pneumoconiosis screening and staging using chest radiographs. The model, based on chest radiographs, was developed using a training cohort and validated using an independent test cohort. Every i...
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Nature Portfolio
2021
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oai:doaj.org-article:db1cc265bd9a4042b7367f6d6b28f3452021-12-02T10:48:13ZA deep learning-based model for screening and staging pneumoconiosis10.1038/s41598-020-77924-z2045-2322https://doaj.org/article/db1cc265bd9a4042b7367f6d6b28f3452021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-77924-zhttps://doaj.org/toc/2045-2322Abstract This study aims to develop an artificial intelligence (AI)-based model to assist radiologists in pneumoconiosis screening and staging using chest radiographs. The model, based on chest radiographs, was developed using a training cohort and validated using an independent test cohort. Every image in the training and test datasets were labeled by experienced radiologists in a double-blinded fashion. The computational model started by segmenting the lung field into six subregions. Then, convolutional neural network classification model was used to predict the opacity level for each subregion respectively. Finally, the diagnosis for each subject (normal, stage I, II, or III pneumoconiosis) was determined by summarizing the subregion-based prediction results. For the independent test cohort, pneumoconiosis screening accuracy was 0.973, with both sensitivity and specificity greater than 0.97. The accuracy for pneumoconiosis staging was 0.927, better than that achieved by two groups of radiologists (0.87 and 0.84, respectively). This study develops a deep learning-based model for screening and staging of pneumoconiosis using man-annotated chest radiographs. The model outperformed two groups of radiologists in the accuracy of pneumoconiosis staging. This pioneer work demonstrates the feasibility and efficiency of AI-assisted radiography screening and diagnosis in occupational lung diseases.Liuzhuo ZhangRuichen RongQiwei LiDonghan M. YangBo YaoDanni LuoXiong ZhangXianfeng ZhuJun LuoYongquan LiuXinyue YangXiang JiZhidong LiuYang XieYan ShaZhimin LiGuanghua XiaoNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021) |
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DOAJ |
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DOAJ |
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EN |
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Medicine R Science Q |
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Medicine R Science Q Liuzhuo Zhang Ruichen Rong Qiwei Li Donghan M. Yang Bo Yao Danni Luo Xiong Zhang Xianfeng Zhu Jun Luo Yongquan Liu Xinyue Yang Xiang Ji Zhidong Liu Yang Xie Yan Sha Zhimin Li Guanghua Xiao A deep learning-based model for screening and staging pneumoconiosis |
| description |
Abstract This study aims to develop an artificial intelligence (AI)-based model to assist radiologists in pneumoconiosis screening and staging using chest radiographs. The model, based on chest radiographs, was developed using a training cohort and validated using an independent test cohort. Every image in the training and test datasets were labeled by experienced radiologists in a double-blinded fashion. The computational model started by segmenting the lung field into six subregions. Then, convolutional neural network classification model was used to predict the opacity level for each subregion respectively. Finally, the diagnosis for each subject (normal, stage I, II, or III pneumoconiosis) was determined by summarizing the subregion-based prediction results. For the independent test cohort, pneumoconiosis screening accuracy was 0.973, with both sensitivity and specificity greater than 0.97. The accuracy for pneumoconiosis staging was 0.927, better than that achieved by two groups of radiologists (0.87 and 0.84, respectively). This study develops a deep learning-based model for screening and staging of pneumoconiosis using man-annotated chest radiographs. The model outperformed two groups of radiologists in the accuracy of pneumoconiosis staging. This pioneer work demonstrates the feasibility and efficiency of AI-assisted radiography screening and diagnosis in occupational lung diseases. |
| format |
article |
| author |
Liuzhuo Zhang Ruichen Rong Qiwei Li Donghan M. Yang Bo Yao Danni Luo Xiong Zhang Xianfeng Zhu Jun Luo Yongquan Liu Xinyue Yang Xiang Ji Zhidong Liu Yang Xie Yan Sha Zhimin Li Guanghua Xiao |
| author_facet |
Liuzhuo Zhang Ruichen Rong Qiwei Li Donghan M. Yang Bo Yao Danni Luo Xiong Zhang Xianfeng Zhu Jun Luo Yongquan Liu Xinyue Yang Xiang Ji Zhidong Liu Yang Xie Yan Sha Zhimin Li Guanghua Xiao |
| author_sort |
Liuzhuo Zhang |
| title |
A deep learning-based model for screening and staging pneumoconiosis |
| title_short |
A deep learning-based model for screening and staging pneumoconiosis |
| title_full |
A deep learning-based model for screening and staging pneumoconiosis |
| title_fullStr |
A deep learning-based model for screening and staging pneumoconiosis |
| title_full_unstemmed |
A deep learning-based model for screening and staging pneumoconiosis |
| title_sort |
deep learning-based model for screening and staging pneumoconiosis |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/db1cc265bd9a4042b7367f6d6b28f345 |
| work_keys_str_mv |
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