Recent ultrasound advancements for the manipulation of nanobiomaterials and nanoformulations for drug delivery

Recent advances in ultrasound (US) have shown its great potential in biomedical applications as diagnostic and therapeutic tools. The coupling of US-assisted drug delivery systems with nanobiomaterials possessing tailor-made functions has been shown to remove the limitations of conventional drug del...

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Autores principales:	Sze Shin Low, Chang Nong Lim, Maxine Yew, Wai Siong Chai, Liang Ee Low, Sivakumar Manickam, Beng Ti Tey, Pau Loke Show
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Ultrasound Drug delivery Nanobiomaterial Disease COVID-19 Chemistry QD1-999 Acoustics. Sound QC221-246
Acceso en línea:	https://doaj.org/article/db1ed53dbe5340278ca6607858574cc1
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spelling	oai:doaj.org-article:db1ed53dbe5340278ca6607858574cc12021-12-02T04:59:46ZRecent ultrasound advancements for the manipulation of nanobiomaterials and nanoformulations for drug delivery1350-417710.1016/j.ultsonch.2021.105805https://doaj.org/article/db1ed53dbe5340278ca6607858574cc12021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1350417721003473https://doaj.org/toc/1350-4177Recent advances in ultrasound (US) have shown its great potential in biomedical applications as diagnostic and therapeutic tools. The coupling of US-assisted drug delivery systems with nanobiomaterials possessing tailor-made functions has been shown to remove the limitations of conventional drug delivery systems. The low-frequency US has significantly enhanced the targeted drug delivery effect and efficacy, reducing limitations posed by conventional treatments such as a limited therapeutic window. The acoustic cavitation effect induced by the US-mediated microbubbles (MBs) has been reported to replace drugs in certain acute diseases such as ischemic stroke. This review briefly discusses the US principles, with particular attention to the recent advancements in drug delivery applications. Furthermore, US-assisted drug delivery coupled with nanobiomaterials to treat different diseases (cancer, neurodegenerative disease, diabetes, thrombosis, and COVID-19) are discussed in detail. Finally, this review covers the future perspectives and challenges on the applications of US-mediated nanobiomaterials.Sze Shin LowChang Nong LimMaxine YewWai Siong ChaiLiang Ee LowSivakumar ManickamBeng Ti TeyPau Loke ShowElsevierarticleUltrasoundDrug deliveryNanobiomaterialDiseaseCOVID-19ChemistryQD1-999Acoustics. SoundQC221-246ENUltrasonics Sonochemistry, Vol 80, Iss , Pp 105805- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ultrasound Drug delivery Nanobiomaterial Disease COVID-19 Chemistry QD1-999 Acoustics. Sound QC221-246
spellingShingle	Ultrasound Drug delivery Nanobiomaterial Disease COVID-19 Chemistry QD1-999 Acoustics. Sound QC221-246 Sze Shin Low Chang Nong Lim Maxine Yew Wai Siong Chai Liang Ee Low Sivakumar Manickam Beng Ti Tey Pau Loke Show Recent ultrasound advancements for the manipulation of nanobiomaterials and nanoformulations for drug delivery
description	Recent advances in ultrasound (US) have shown its great potential in biomedical applications as diagnostic and therapeutic tools. The coupling of US-assisted drug delivery systems with nanobiomaterials possessing tailor-made functions has been shown to remove the limitations of conventional drug delivery systems. The low-frequency US has significantly enhanced the targeted drug delivery effect and efficacy, reducing limitations posed by conventional treatments such as a limited therapeutic window. The acoustic cavitation effect induced by the US-mediated microbubbles (MBs) has been reported to replace drugs in certain acute diseases such as ischemic stroke. This review briefly discusses the US principles, with particular attention to the recent advancements in drug delivery applications. Furthermore, US-assisted drug delivery coupled with nanobiomaterials to treat different diseases (cancer, neurodegenerative disease, diabetes, thrombosis, and COVID-19) are discussed in detail. Finally, this review covers the future perspectives and challenges on the applications of US-mediated nanobiomaterials.
format	article
author	Sze Shin Low Chang Nong Lim Maxine Yew Wai Siong Chai Liang Ee Low Sivakumar Manickam Beng Ti Tey Pau Loke Show
author_facet	Sze Shin Low Chang Nong Lim Maxine Yew Wai Siong Chai Liang Ee Low Sivakumar Manickam Beng Ti Tey Pau Loke Show
author_sort	Sze Shin Low
title	Recent ultrasound advancements for the manipulation of nanobiomaterials and nanoformulations for drug delivery
title_short	Recent ultrasound advancements for the manipulation of nanobiomaterials and nanoformulations for drug delivery
title_full	Recent ultrasound advancements for the manipulation of nanobiomaterials and nanoformulations for drug delivery
title_fullStr	Recent ultrasound advancements for the manipulation of nanobiomaterials and nanoformulations for drug delivery
title_full_unstemmed	Recent ultrasound advancements for the manipulation of nanobiomaterials and nanoformulations for drug delivery
title_sort	recent ultrasound advancements for the manipulation of nanobiomaterials and nanoformulations for drug delivery
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/db1ed53dbe5340278ca6607858574cc1
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Recent ultrasound advancements for the manipulation of nanobiomaterials and nanoformulations for drug delivery

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