Optogenetic rewiring of thalamocortical circuits to restore function in the stroke injured brain

Stroke recovery requires circuit reorganization and therapeutic efforts have focused on rewiring cortical circuits after stroke, but what about thalamic inputs? Here, the authors examine how thalamocortical axons are affected by stroke and use optogenetic stimulation to promote recovery.

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Detalles Bibliográficos
Autores principales: Kelly A. Tennant, Stephanie L. Taylor, Emily R. White, Craig E. Brown
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/db209f575c4e42c89a82439cd37297d5
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Sumario:Stroke recovery requires circuit reorganization and therapeutic efforts have focused on rewiring cortical circuits after stroke, but what about thalamic inputs? Here, the authors examine how thalamocortical axons are affected by stroke and use optogenetic stimulation to promote recovery.