HIF-1α hampers dendritic cell function and Th1 generation during chronic visceral leishmaniasis
Abstract Inflammation, although responsible for controlling infection, is often associated with the pathogenesis of chronic diseases. Leishmania donovani, the causative agent of visceral leishmaniasis, induces a strong inflammatory response that leads to splenomegaly and ultimately immune suppressio...
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Main Authors: | Akil Hammami, Belma Melda Abidin, Krista M. Heinonen, Simona Stäger |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Online Access: | https://doaj.org/article/db28a9d99446473bb1a7cbda14e13b25 |
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