HIF-1α hampers dendritic cell function and Th1 generation during chronic visceral leishmaniasis

Abstract Inflammation, although responsible for controlling infection, is often associated with the pathogenesis of chronic diseases. Leishmania donovani, the causative agent of visceral leishmaniasis, induces a strong inflammatory response that leads to splenomegaly and ultimately immune suppressio...

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Bibliographic Details
Main Authors: Akil Hammami, Belma Melda Abidin, Krista M. Heinonen, Simona Stäger
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
R
Q
Online Access:https://doaj.org/article/db28a9d99446473bb1a7cbda14e13b25
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