In vitro implementation of robust gene regulation in a synthetic biomolecular integral controller
Feedback mechanisms for synthetic gene circuits are necessary to provide robustness to external perturbations. Here the authors validate a biomolecular controller based on a sigma and anti-sigma factor to achieve stable gene expression in the face of external disturbances in an in vitro synthetic ge...
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Autores principales: | Deepak K. Agrawal, Ryan Marshall, Vincent Noireaux, Eduardo D Sontag |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/db296cdc1e4f40eeb70fd1ef4b8ff017 |
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