Visuospatial working memory dysfunction from tapping span test as a diagnostic tool for patients with mild posterior cortical atrophy

Abstract Posterior cortical atrophy is a rare degenerative condition with prominent visuospatial dysfunction which commonly occurs between ages 50 and 65. A diagnosis of mild posterior cortical atrophy sometimes challenging and can be delayed because there are currently no established neuropsycholog...

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Autores principales:	Michitaka Funayama, Taketo Takata, Yoshitaka Nakagawa, Kosaku Sunagawa, Asuka Nakajima, Hiroaki Kawashima, Masaru Mimura
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/db3157230f464455a3681b19c0b1de7d
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spelling	oai:doaj.org-article:db3157230f464455a3681b19c0b1de7d2021-12-02T16:51:26ZVisuospatial working memory dysfunction from tapping span test as a diagnostic tool for patients with mild posterior cortical atrophy10.1038/s41598-021-90159-w2045-2322https://doaj.org/article/db3157230f464455a3681b19c0b1de7d2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-90159-whttps://doaj.org/toc/2045-2322Abstract Posterior cortical atrophy is a rare degenerative condition with prominent visuospatial dysfunction which commonly occurs between ages 50 and 65. A diagnosis of mild posterior cortical atrophy sometimes challenging and can be delayed because there are currently no established neuropsychological examination methods that can easily be used in clinical settings. In this study, we examined whether the tapping span test is a potential diagnostic tool for posterior cortical atrophy and what impairment the tapping span test is indicative of in this condition. Eight patients with mild posterior cortical atrophy were recruited. Age- and severity-matched individuals with amnesic Alzheimer’s disease (n = 9) were also recruited as a control group. The participants were subjected to the tapping span test and several visuospatial working memory tests. The results of the tapping span and visuospatial working memory tests were worse for the posterior cortical atrophy group when compared with the control group. The results from the tapping span tests were strongly correlated with those from the visuospatial working memory tests. The tapping span test is a simple and potentially useful diagnostic tool for patients with mild posterior cortical atrophy, as it reflects visuospatial working memory function.Michitaka FunayamaTaketo TakataYoshitaka NakagawaKosaku SunagawaAsuka NakajimaHiroaki KawashimaMasaru MimuraNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Michitaka Funayama Taketo Takata Yoshitaka Nakagawa Kosaku Sunagawa Asuka Nakajima Hiroaki Kawashima Masaru Mimura Visuospatial working memory dysfunction from tapping span test as a diagnostic tool for patients with mild posterior cortical atrophy
description	Abstract Posterior cortical atrophy is a rare degenerative condition with prominent visuospatial dysfunction which commonly occurs between ages 50 and 65. A diagnosis of mild posterior cortical atrophy sometimes challenging and can be delayed because there are currently no established neuropsychological examination methods that can easily be used in clinical settings. In this study, we examined whether the tapping span test is a potential diagnostic tool for posterior cortical atrophy and what impairment the tapping span test is indicative of in this condition. Eight patients with mild posterior cortical atrophy were recruited. Age- and severity-matched individuals with amnesic Alzheimer’s disease (n = 9) were also recruited as a control group. The participants were subjected to the tapping span test and several visuospatial working memory tests. The results of the tapping span and visuospatial working memory tests were worse for the posterior cortical atrophy group when compared with the control group. The results from the tapping span tests were strongly correlated with those from the visuospatial working memory tests. The tapping span test is a simple and potentially useful diagnostic tool for patients with mild posterior cortical atrophy, as it reflects visuospatial working memory function.
format	article
author	Michitaka Funayama Taketo Takata Yoshitaka Nakagawa Kosaku Sunagawa Asuka Nakajima Hiroaki Kawashima Masaru Mimura
author_facet	Michitaka Funayama Taketo Takata Yoshitaka Nakagawa Kosaku Sunagawa Asuka Nakajima Hiroaki Kawashima Masaru Mimura
author_sort	Michitaka Funayama
title	Visuospatial working memory dysfunction from tapping span test as a diagnostic tool for patients with mild posterior cortical atrophy
title_short	Visuospatial working memory dysfunction from tapping span test as a diagnostic tool for patients with mild posterior cortical atrophy
title_full	Visuospatial working memory dysfunction from tapping span test as a diagnostic tool for patients with mild posterior cortical atrophy
title_fullStr	Visuospatial working memory dysfunction from tapping span test as a diagnostic tool for patients with mild posterior cortical atrophy
title_full_unstemmed	Visuospatial working memory dysfunction from tapping span test as a diagnostic tool for patients with mild posterior cortical atrophy
title_sort	visuospatial working memory dysfunction from tapping span test as a diagnostic tool for patients with mild posterior cortical atrophy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/db3157230f464455a3681b19c0b1de7d
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Visuospatial working memory dysfunction from tapping span test as a diagnostic tool for patients with mild posterior cortical atrophy

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