Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis

Mass spectrometry facilitates large-scale glycosylation profiling but in-depth analysis of intact glycopeptides is still challenging. Here, the authors show that activated ion electron transfer dissociation is suitable for glycopeptide fragmentation and improves glycoproteome coverage.

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Autores principales: Nicholas M. Riley, Alexander S. Hebert, Michael S. Westphall, Joshua J. Coon
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/db34920cf377464b93976745b85dbd71
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