Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis
Mass spectrometry facilitates large-scale glycosylation profiling but in-depth analysis of intact glycopeptides is still challenging. Here, the authors show that activated ion electron transfer dissociation is suitable for glycopeptide fragmentation and improves glycoproteome coverage.
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Autores principales: | Nicholas M. Riley, Alexander S. Hebert, Michael S. Westphall, Joshua J. Coon |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/db34920cf377464b93976745b85dbd71 |
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