Lamin A/C is a risk biomarker in colorectal cancer.
<h4>Background</h4>A-type lamins are type V intermediate filament proteins encoded by the gene LMNA. Mutations in LMNA give rise to diverse degenerative diseases related to premature ageing. A-type lamins also influence the activity of the Retinoblastoma protein (pRb) and oncogenes such...
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Main Authors: | Naomi D Willis, Thomas R Cox, Syed F Rahman-Casañs, Kim Smits, Stefan A Przyborski, Piet van den Brandt, Manon van Engeland, Matty Weijenberg, Robert G Wilson, Adriaan de Bruïne, Christopher J Hutchison |
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Format: | article |
Language: | EN |
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Public Library of Science (PLoS)
2008
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Online Access: | https://doaj.org/article/db3d2cfb44af49da8812d1846bf6a64c |
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