Length-dependent changes of lower limb muscle morphology in Chronic Inflammatory Demyelinating Polyneuropathy assessed with magnetic resonance imaging

The objective of the present study was to assess muscle quantity of the thigh and leg in patients with chronic inflammatory demyelinating polyneuropathy (CIDP) compared to age and sex matched controls in exploring length-dependent changes of innervated muscles. In five people with CIDP and seven co...

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Autores principales:	Jacob Fanous, Alexander M. Zero, Kevin J. Gilmore, Timothy J. Doherty, Charles Rice
Formato:	article
Lenguaje:	EN
Publicado:	PAGEPress Publications 2021
Materias:	Chronic inflammatory demyelinating polyneuropathy CIDP muscle quality muscle composition MRI Medicine R Human anatomy QM1-695
Acceso en línea:	https://doaj.org/article/db405c4def1f49528a6ffd61428620c6
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spelling	oai:doaj.org-article:db405c4def1f49528a6ffd61428620c62021-11-18T21:38:53ZLength-dependent changes of lower limb muscle morphology in Chronic Inflammatory Demyelinating Polyneuropathy assessed with magnetic resonance imaging10.4081/ejtm.2021.102002037-74522037-7460https://doaj.org/article/db405c4def1f49528a6ffd61428620c62021-11-01T00:00:00Zhttps://www.pagepressjournals.org/index.php/bam/article/view/10200https://doaj.org/toc/2037-7452https://doaj.org/toc/2037-7460 The objective of the present study was to assess muscle quantity of the thigh and leg in patients with chronic inflammatory demyelinating polyneuropathy (CIDP) compared to age and sex matched controls in exploring length-dependent changes of innervated muscles. In five people with CIDP and seven controls, magnetic resonance imaging was used to assess muscle morphology of the four parts of the quadriceps and medial hamstring muscles. Findings were compared to the triceps surae from a subset of participants. The CIDP group had less contractile tissue in the quadriceps (11.5%, P<0.05), hamstrings (15.6%, P<0.05) and triceps surae (35.9%, P<0.05) compared to controls. Additionally, CIDP had less contractile tissue (18.7%) in the triceps surae compared to the hamstrings (P<0.05). Muscle quantity in the quadriceps and hamstrings in CIDP was less than controls, but differences were greater for the distal triceps surae. These findings support a length-dependent affect of CIDP on limb musculature composition. Jacob FanousAlexander M. ZeroKevin J. GilmoreTimothy J. DohertyCharles RicePAGEPress PublicationsarticleChronic inflammatory demyelinating polyneuropathyCIDPmuscle qualitymuscle compositionMRIMedicineRHuman anatomyQM1-695ENEuropean Journal of Translational Myology (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Chronic inflammatory demyelinating polyneuropathy CIDP muscle quality muscle composition MRI Medicine R Human anatomy QM1-695
spellingShingle	Chronic inflammatory demyelinating polyneuropathy CIDP muscle quality muscle composition MRI Medicine R Human anatomy QM1-695 Jacob Fanous Alexander M. Zero Kevin J. Gilmore Timothy J. Doherty Charles Rice Length-dependent changes of lower limb muscle morphology in Chronic Inflammatory Demyelinating Polyneuropathy assessed with magnetic resonance imaging
description	The objective of the present study was to assess muscle quantity of the thigh and leg in patients with chronic inflammatory demyelinating polyneuropathy (CIDP) compared to age and sex matched controls in exploring length-dependent changes of innervated muscles. In five people with CIDP and seven controls, magnetic resonance imaging was used to assess muscle morphology of the four parts of the quadriceps and medial hamstring muscles. Findings were compared to the triceps surae from a subset of participants. The CIDP group had less contractile tissue in the quadriceps (11.5%, P<0.05), hamstrings (15.6%, P<0.05) and triceps surae (35.9%, P<0.05) compared to controls. Additionally, CIDP had less contractile tissue (18.7%) in the triceps surae compared to the hamstrings (P<0.05). Muscle quantity in the quadriceps and hamstrings in CIDP was less than controls, but differences were greater for the distal triceps surae. These findings support a length-dependent affect of CIDP on limb musculature composition.
format	article
author	Jacob Fanous Alexander M. Zero Kevin J. Gilmore Timothy J. Doherty Charles Rice
author_facet	Jacob Fanous Alexander M. Zero Kevin J. Gilmore Timothy J. Doherty Charles Rice
author_sort	Jacob Fanous
title	Length-dependent changes of lower limb muscle morphology in Chronic Inflammatory Demyelinating Polyneuropathy assessed with magnetic resonance imaging
title_short	Length-dependent changes of lower limb muscle morphology in Chronic Inflammatory Demyelinating Polyneuropathy assessed with magnetic resonance imaging
title_full	Length-dependent changes of lower limb muscle morphology in Chronic Inflammatory Demyelinating Polyneuropathy assessed with magnetic resonance imaging
title_fullStr	Length-dependent changes of lower limb muscle morphology in Chronic Inflammatory Demyelinating Polyneuropathy assessed with magnetic resonance imaging
title_full_unstemmed	Length-dependent changes of lower limb muscle morphology in Chronic Inflammatory Demyelinating Polyneuropathy assessed with magnetic resonance imaging
title_sort	length-dependent changes of lower limb muscle morphology in chronic inflammatory demyelinating polyneuropathy assessed with magnetic resonance imaging
publisher	PAGEPress Publications
publishDate	2021
url	https://doaj.org/article/db405c4def1f49528a6ffd61428620c6
work_keys_str_mv	AT jacobfanous lengthdependentchangesoflowerlimbmusclemorphologyinchronicinflammatorydemyelinatingpolyneuropathyassessedwithmagneticresonanceimaging AT alexandermzero lengthdependentchangesoflowerlimbmusclemorphologyinchronicinflammatorydemyelinatingpolyneuropathyassessedwithmagneticresonanceimaging AT kevinjgilmore lengthdependentchangesoflowerlimbmusclemorphologyinchronicinflammatorydemyelinatingpolyneuropathyassessedwithmagneticresonanceimaging AT timothyjdoherty lengthdependentchangesoflowerlimbmusclemorphologyinchronicinflammatorydemyelinatingpolyneuropathyassessedwithmagneticresonanceimaging AT charlesrice lengthdependentchangesoflowerlimbmusclemorphologyinchronicinflammatorydemyelinatingpolyneuropathyassessedwithmagneticresonanceimaging
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Length-dependent changes of lower limb muscle morphology in Chronic Inflammatory Demyelinating Polyneuropathy assessed with magnetic resonance imaging

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