Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex
Fast spiking interneurons provide perisomatic inhibition in the cortex. Here, Baohan et al. show the failure to develop perisomatic inhibition in heterozygous PTENnull mutant mouse and the underlying mechanism to EphB4 reduction in an experience-dependent manner.
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Nature Portfolio
2016
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oai:doaj.org-article:db441d1bba9e472a87afede6837860652021-12-02T17:31:34ZPten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex10.1038/ncomms128292041-1723https://doaj.org/article/db441d1bba9e472a87afede6837860652016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12829https://doaj.org/toc/2041-1723Fast spiking interneurons provide perisomatic inhibition in the cortex. Here, Baohan et al. show the failure to develop perisomatic inhibition in heterozygous PTENnull mutant mouse and the underlying mechanism to EphB4 reduction in an experience-dependent manner.Amy BaohanTaruna IkrarElaine TringXiangmin XuJoshua T. TrachtenbergNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016) |
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Science Q Amy Baohan Taruna Ikrar Elaine Tring Xiangmin Xu Joshua T. Trachtenberg Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex |
description |
Fast spiking interneurons provide perisomatic inhibition in the cortex. Here, Baohan et al. show the failure to develop perisomatic inhibition in heterozygous PTENnull mutant mouse and the underlying mechanism to EphB4 reduction in an experience-dependent manner. |
format |
article |
author |
Amy Baohan Taruna Ikrar Elaine Tring Xiangmin Xu Joshua T. Trachtenberg |
author_facet |
Amy Baohan Taruna Ikrar Elaine Tring Xiangmin Xu Joshua T. Trachtenberg |
author_sort |
Amy Baohan |
title |
Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex |
title_short |
Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex |
title_full |
Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex |
title_fullStr |
Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex |
title_full_unstemmed |
Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex |
title_sort |
pten and ephb4 regulate the establishment of perisomatic inhibition in mouse visual cortex |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/db441d1bba9e472a87afede683786065 |
work_keys_str_mv |
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_version_ |
1718380584059797504 |