Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex

Fast spiking interneurons provide perisomatic inhibition in the cortex. Here, Baohan et al. show the failure to develop perisomatic inhibition in heterozygous PTENnull mutant mouse and the underlying mechanism to EphB4 reduction in an experience-dependent manner.

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Autores principales: Amy Baohan, Taruna Ikrar, Elaine Tring, Xiangmin Xu, Joshua T. Trachtenberg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/db441d1bba9e472a87afede683786065
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spelling oai:doaj.org-article:db441d1bba9e472a87afede6837860652021-12-02T17:31:34ZPten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex10.1038/ncomms128292041-1723https://doaj.org/article/db441d1bba9e472a87afede6837860652016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12829https://doaj.org/toc/2041-1723Fast spiking interneurons provide perisomatic inhibition in the cortex. Here, Baohan et al. show the failure to develop perisomatic inhibition in heterozygous PTENnull mutant mouse and the underlying mechanism to EphB4 reduction in an experience-dependent manner.Amy BaohanTaruna IkrarElaine TringXiangmin XuJoshua T. TrachtenbergNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Amy Baohan
Taruna Ikrar
Elaine Tring
Xiangmin Xu
Joshua T. Trachtenberg
Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex
description Fast spiking interneurons provide perisomatic inhibition in the cortex. Here, Baohan et al. show the failure to develop perisomatic inhibition in heterozygous PTENnull mutant mouse and the underlying mechanism to EphB4 reduction in an experience-dependent manner.
format article
author Amy Baohan
Taruna Ikrar
Elaine Tring
Xiangmin Xu
Joshua T. Trachtenberg
author_facet Amy Baohan
Taruna Ikrar
Elaine Tring
Xiangmin Xu
Joshua T. Trachtenberg
author_sort Amy Baohan
title Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex
title_short Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex
title_full Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex
title_fullStr Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex
title_full_unstemmed Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex
title_sort pten and ephb4 regulate the establishment of perisomatic inhibition in mouse visual cortex
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/db441d1bba9e472a87afede683786065
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AT elainetring ptenandephb4regulatetheestablishmentofperisomaticinhibitioninmousevisualcortex
AT xiangminxu ptenandephb4regulatetheestablishmentofperisomaticinhibitioninmousevisualcortex
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