Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis

Beta3-adrenergic receptor signaling regulates adipose tissue browning. Here, the authors show that barr2 regulates internalization of beta3-adrenergic receptors and that mice lacking barr2 in adipocytes are protected from diet-induced weight gain and metabolic complications.

Guardado en:

Detalles Bibliográficos
Autores principales:	Sai P. Pydi, Shanu Jain, Wesley Tung, Yinghong Cui, Lu Zhu, Wataru Sakamoto, Shalini Jain, Brent S. Abel, Monica C. Skarulis, Jie Liu, Thanh Huynh, Karel Pacak, Marc G. Caron, Oksana Gavrilova, Toren Finkel, Jürgen Wess
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/db4766c456f2475085560b5fbc6645dc
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:db4766c456f2475085560b5fbc6645dc
record_format	dspace
spelling	oai:doaj.org-article:db4766c456f2475085560b5fbc6645dc2021-12-02T14:39:19ZAdipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis10.1038/s41467-019-11003-42041-1723https://doaj.org/article/db4766c456f2475085560b5fbc6645dc2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11003-4https://doaj.org/toc/2041-1723Beta3-adrenergic receptor signaling regulates adipose tissue browning. Here, the authors show that barr2 regulates internalization of beta3-adrenergic receptors and that mice lacking barr2 in adipocytes are protected from diet-induced weight gain and metabolic complications.Sai P. PydiShanu JainWesley TungYinghong CuiLu ZhuWataru SakamotoShalini JainBrent S. AbelMonica C. SkarulisJie LiuThanh HuynhKarel PacakMarc G. CaronOksana GavrilovaToren FinkelJürgen WessNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sai P. Pydi Shanu Jain Wesley Tung Yinghong Cui Lu Zhu Wataru Sakamoto Shalini Jain Brent S. Abel Monica C. Skarulis Jie Liu Thanh Huynh Karel Pacak Marc G. Caron Oksana Gavrilova Toren Finkel Jürgen Wess Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis
description	Beta3-adrenergic receptor signaling regulates adipose tissue browning. Here, the authors show that barr2 regulates internalization of beta3-adrenergic receptors and that mice lacking barr2 in adipocytes are protected from diet-induced weight gain and metabolic complications.
format	article
author	Sai P. Pydi Shanu Jain Wesley Tung Yinghong Cui Lu Zhu Wataru Sakamoto Shalini Jain Brent S. Abel Monica C. Skarulis Jie Liu Thanh Huynh Karel Pacak Marc G. Caron Oksana Gavrilova Toren Finkel Jürgen Wess
author_facet	Sai P. Pydi Shanu Jain Wesley Tung Yinghong Cui Lu Zhu Wataru Sakamoto Shalini Jain Brent S. Abel Monica C. Skarulis Jie Liu Thanh Huynh Karel Pacak Marc G. Caron Oksana Gavrilova Toren Finkel Jürgen Wess
author_sort	Sai P. Pydi
title	Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis
title_short	Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis
title_full	Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis
title_fullStr	Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis
title_full_unstemmed	Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis
title_sort	adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/db4766c456f2475085560b5fbc6645dc
work_keys_str_mv	AT saippydi adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis AT shanujain adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis AT wesleytung adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis AT yinghongcui adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis AT luzhu adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis AT watarusakamoto adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis AT shalinijain adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis AT brentsabel adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis AT monicacskarulis adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis AT jieliu adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis AT thanhhuynh adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis AT karelpacak adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis AT marcgcaron adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis AT oksanagavrilova adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis AT torenfinkel adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis AT jurgenwess adipocytebarrestin2isessentialformaintainingwholebodyglucoseandenergyhomeostasis
_version_	1718390684008841216

Adipocyte β-arrestin-2 is essential for maintaining whole body glucose and energy homeostasis

Ejemplares similares