Evolutionary genetics of immunological supertypes reveals two faces of the Red Queen

Host-parasite coevolution can lead to arms races favouring novel immunogenetic alleles or the maintenance of diversity in a balanced polymorphism. Here, Lighten et al. combine data on MHC diversity across three guppy species and simulations to show that polymorphisms of immunogenetic supertypes may...

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Autores principales: Jackie Lighten, Alexander S. T. Papadopulos, Ryan S. Mohammed, Ben J. Ward, Ian G. Paterson, Lyndsey Baillie, Ian R. Bradbury, Andrew P. Hendry, Paul Bentzen, Cock van Oosterhout
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/db49789d941e4957b4eb89088657f6bb
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Sumario:Host-parasite coevolution can lead to arms races favouring novel immunogenetic alleles or the maintenance of diversity in a balanced polymorphism. Here, Lighten et al. combine data on MHC diversity across three guppy species and simulations to show that polymorphisms of immunogenetic supertypes may persist even as alleles within supertypes are involved in an arms race.