Evolutionary genetics of immunological supertypes reveals two faces of the Red Queen
Host-parasite coevolution can lead to arms races favouring novel immunogenetic alleles or the maintenance of diversity in a balanced polymorphism. Here, Lighten et al. combine data on MHC diversity across three guppy species and simulations to show that polymorphisms of immunogenetic supertypes may...
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Nature Portfolio
2017
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oai:doaj.org-article:db49789d941e4957b4eb89088657f6bb2021-12-02T16:51:42ZEvolutionary genetics of immunological supertypes reveals two faces of the Red Queen10.1038/s41467-017-01183-22041-1723https://doaj.org/article/db49789d941e4957b4eb89088657f6bb2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01183-2https://doaj.org/toc/2041-1723Host-parasite coevolution can lead to arms races favouring novel immunogenetic alleles or the maintenance of diversity in a balanced polymorphism. Here, Lighten et al. combine data on MHC diversity across three guppy species and simulations to show that polymorphisms of immunogenetic supertypes may persist even as alleles within supertypes are involved in an arms race.Jackie LightenAlexander S. T. PapadopulosRyan S. MohammedBen J. WardIan G. PatersonLyndsey BaillieIan R. BradburyAndrew P. HendryPaul BentzenCock van OosterhoutNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
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Science Q Jackie Lighten Alexander S. T. Papadopulos Ryan S. Mohammed Ben J. Ward Ian G. Paterson Lyndsey Baillie Ian R. Bradbury Andrew P. Hendry Paul Bentzen Cock van Oosterhout Evolutionary genetics of immunological supertypes reveals two faces of the Red Queen |
description |
Host-parasite coevolution can lead to arms races favouring novel immunogenetic alleles or the maintenance of diversity in a balanced polymorphism. Here, Lighten et al. combine data on MHC diversity across three guppy species and simulations to show that polymorphisms of immunogenetic supertypes may persist even as alleles within supertypes are involved in an arms race. |
format |
article |
author |
Jackie Lighten Alexander S. T. Papadopulos Ryan S. Mohammed Ben J. Ward Ian G. Paterson Lyndsey Baillie Ian R. Bradbury Andrew P. Hendry Paul Bentzen Cock van Oosterhout |
author_facet |
Jackie Lighten Alexander S. T. Papadopulos Ryan S. Mohammed Ben J. Ward Ian G. Paterson Lyndsey Baillie Ian R. Bradbury Andrew P. Hendry Paul Bentzen Cock van Oosterhout |
author_sort |
Jackie Lighten |
title |
Evolutionary genetics of immunological supertypes reveals two faces of the Red Queen |
title_short |
Evolutionary genetics of immunological supertypes reveals two faces of the Red Queen |
title_full |
Evolutionary genetics of immunological supertypes reveals two faces of the Red Queen |
title_fullStr |
Evolutionary genetics of immunological supertypes reveals two faces of the Red Queen |
title_full_unstemmed |
Evolutionary genetics of immunological supertypes reveals two faces of the Red Queen |
title_sort |
evolutionary genetics of immunological supertypes reveals two faces of the red queen |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/db49789d941e4957b4eb89088657f6bb |
work_keys_str_mv |
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1718382948579803136 |