FREQUENCY AND PATTERN OF DYSLIPIDEMIA IN CHILDREN WITH END STAGE RENAL DISEASE

Objective: To determine the frequency and pattern of dyslipidemia in pediatric patients with end stage renal disease presenting in a tertiary care hospital. Study Design: Cross-sectional, observational study. Place and Duration of Study: The Children's hospital and the Institute of Child...

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Autores principales:	Adeela Chaudhry, Farkhanda Hafeez, Naureen Akhtar, Uzma Shehzadi
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2019
Materias:	chronic kidney disease dyslipidemia Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/db4a06392c0b4fcebb5d105a1a0c6620
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spelling	oai:doaj.org-article:db4a06392c0b4fcebb5d105a1a0c66202021-11-12T02:45:21ZFREQUENCY AND PATTERN OF DYSLIPIDEMIA IN CHILDREN WITH END STAGE RENAL DISEASE0030-96482411-8842https://doaj.org/article/db4a06392c0b4fcebb5d105a1a0c66202019-06-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/3018/2256https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine the frequency and pattern of dyslipidemia in pediatric patients with end stage renal disease presenting in a tertiary care hospital. Study Design: Cross-sectional, observational study. Place and Duration of Study: The Children's hospital and the Institute of Child Health Lahore, from Sep 2016 to Nov 2017. Material and Methods: Children aged 5-15 years, of either gender and diagnosed with end stage renal disease were selected for the study. All the patients were undergoing renal replacement therapy in the form of hemodialysis and/or continuous ambulatory peritoneal dialysis. The serum levels of total cholesterol, triglycerides, high density lipoprotein, low density lipoprotein and very low density lipoprotein were measured. Results: There were 138 patients in the study with mean age 11.24 ± 2.37 years and male to female ratio 2.5:1. The mean ± SD values of total serum cholesterol, triglycerides, and low density lipoprotein were found to be 174.0 ± 54.1, 241.2 ± 142.4 and 95.2 ± 49.0 mg/dl respectively. The frequency of abnormally high levels of total serum cholesterol, triglycerides, and low density lipoprotein were found to be 21.7%, 84.8% and 19.6% respectively. The lipid profile of patients on peritoneal dialysis was markedly elevated as compared to that of patients on maintenance hemodialysis (p-value ≤0.05). Conclusion: Majority of pediatric patients with end stage renal disease had suffered from dyslipidemia especially raised serum triglycerides. Timely identification of abnormal lipid levels and appropriate management is expected to help reduce cardiovascular morbidity and mortality associated with dyslipidemia in these pediatric patients. Moreover, lipid profile of patients on peritoneal dialysis was more deranged than those on hemodialysis.Adeela ChaudhryFarkhanda HafeezNaureen AkhtarUzma ShehzadiArmy Medical College Rawalpindiarticlechronic kidney diseasedyslipidemiaMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 3, Pp 510-515 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	chronic kidney disease dyslipidemia Medicine R Medicine (General) R5-920
spellingShingle	chronic kidney disease dyslipidemia Medicine R Medicine (General) R5-920 Adeela Chaudhry Farkhanda Hafeez Naureen Akhtar Uzma Shehzadi FREQUENCY AND PATTERN OF DYSLIPIDEMIA IN CHILDREN WITH END STAGE RENAL DISEASE
description	Objective: To determine the frequency and pattern of dyslipidemia in pediatric patients with end stage renal disease presenting in a tertiary care hospital. Study Design: Cross-sectional, observational study. Place and Duration of Study: The Children's hospital and the Institute of Child Health Lahore, from Sep 2016 to Nov 2017. Material and Methods: Children aged 5-15 years, of either gender and diagnosed with end stage renal disease were selected for the study. All the patients were undergoing renal replacement therapy in the form of hemodialysis and/or continuous ambulatory peritoneal dialysis. The serum levels of total cholesterol, triglycerides, high density lipoprotein, low density lipoprotein and very low density lipoprotein were measured. Results: There were 138 patients in the study with mean age 11.24 ± 2.37 years and male to female ratio 2.5:1. The mean ± SD values of total serum cholesterol, triglycerides, and low density lipoprotein were found to be 174.0 ± 54.1, 241.2 ± 142.4 and 95.2 ± 49.0 mg/dl respectively. The frequency of abnormally high levels of total serum cholesterol, triglycerides, and low density lipoprotein were found to be 21.7%, 84.8% and 19.6% respectively. The lipid profile of patients on peritoneal dialysis was markedly elevated as compared to that of patients on maintenance hemodialysis (p-value ≤0.05). Conclusion: Majority of pediatric patients with end stage renal disease had suffered from dyslipidemia especially raised serum triglycerides. Timely identification of abnormal lipid levels and appropriate management is expected to help reduce cardiovascular morbidity and mortality associated with dyslipidemia in these pediatric patients. Moreover, lipid profile of patients on peritoneal dialysis was more deranged than those on hemodialysis.
format	article
author	Adeela Chaudhry Farkhanda Hafeez Naureen Akhtar Uzma Shehzadi
author_facet	Adeela Chaudhry Farkhanda Hafeez Naureen Akhtar Uzma Shehzadi
author_sort	Adeela Chaudhry
title	FREQUENCY AND PATTERN OF DYSLIPIDEMIA IN CHILDREN WITH END STAGE RENAL DISEASE
title_short	FREQUENCY AND PATTERN OF DYSLIPIDEMIA IN CHILDREN WITH END STAGE RENAL DISEASE
title_full	FREQUENCY AND PATTERN OF DYSLIPIDEMIA IN CHILDREN WITH END STAGE RENAL DISEASE
title_fullStr	FREQUENCY AND PATTERN OF DYSLIPIDEMIA IN CHILDREN WITH END STAGE RENAL DISEASE
title_full_unstemmed	FREQUENCY AND PATTERN OF DYSLIPIDEMIA IN CHILDREN WITH END STAGE RENAL DISEASE
title_sort	frequency and pattern of dyslipidemia in children with end stage renal disease
publisher	Army Medical College Rawalpindi
publishDate	2019
url	https://doaj.org/article/db4a06392c0b4fcebb5d105a1a0c6620
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FREQUENCY AND PATTERN OF DYSLIPIDEMIA IN CHILDREN WITH END STAGE RENAL DISEASE

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