Spaceflight-induced neuroplasticity in humans as measured by MRI: what do we know so far?

Abstract Space travel poses an enormous challenge on the human body; microgravity, ionizing radiation, absence of circadian rhythm, confinement and isolation are just some of the features associated with it. Obviously, all of the latter can have an impact on human physiology and even induce detrimen...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Angelique Van Ombergen, Steven Laureys, Stefan Sunaert, Elena Tomilovskaya, Paul M. Parizel, Floris L. Wuyts
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Biotechnology TP248.13-248.65 Physiology QP1-981
Acceso en línea:	https://doaj.org/article/db5151a5462b422b855f5cf9ecbc9c7f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:db5151a5462b422b855f5cf9ecbc9c7f
record_format	dspace
spelling	oai:doaj.org-article:db5151a5462b422b855f5cf9ecbc9c7f2021-12-02T11:51:09ZSpaceflight-induced neuroplasticity in humans as measured by MRI: what do we know so far?10.1038/s41526-016-0010-82373-8065https://doaj.org/article/db5151a5462b422b855f5cf9ecbc9c7f2017-01-01T00:00:00Zhttps://doi.org/10.1038/s41526-016-0010-8https://doaj.org/toc/2373-8065Abstract Space travel poses an enormous challenge on the human body; microgravity, ionizing radiation, absence of circadian rhythm, confinement and isolation are just some of the features associated with it. Obviously, all of the latter can have an impact on human physiology and even induce detrimental changes. Some organ systems have been studied thoroughly under space conditions, however, not much is known on the functional and morphological effects of spaceflight on the human central nervous system. Previous studies have already shown that central nervous system changes occur during and after spaceflight in the form of neurovestibular problems, alterations in cognitive function and sensory perception, cephalic fluid shifts and psychological disturbances. However, little is known about the underlying neural substrates. In this review, we discuss the current limited knowledge on neuroplastic changes in the human central nervous system associated with spaceflight (actual or simulated) as measured by magnetic resonance imaging-based techniques. Furthermore, we discuss these findings as well as their future perspectives, since this can encourage future research into this delicate and intriguing aspect of spaceflight. Currently, the literature suffers from heterogeneous experimental set-ups and therefore, the lack of comparability of findings among studies. However, the cerebellum, cortical sensorimotor and somatosensory areas and vestibular-related pathways seem to be involved across different studies, suggesting that these brain regions are most affected by (simulated) spaceflight. Extending this knowledge is crucial, especially with the eye on long-duration interplanetary missions (e.g. Mars) and space tourism.Angelique Van OmbergenSteven LaureysStefan SunaertElena TomilovskayaPaul M. ParizelFloris L. WuytsNature PortfolioarticleBiotechnologyTP248.13-248.65PhysiologyQP1-981ENnpj Microgravity, Vol 3, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biotechnology TP248.13-248.65 Physiology QP1-981
spellingShingle	Biotechnology TP248.13-248.65 Physiology QP1-981 Angelique Van Ombergen Steven Laureys Stefan Sunaert Elena Tomilovskaya Paul M. Parizel Floris L. Wuyts Spaceflight-induced neuroplasticity in humans as measured by MRI: what do we know so far?
description	Abstract Space travel poses an enormous challenge on the human body; microgravity, ionizing radiation, absence of circadian rhythm, confinement and isolation are just some of the features associated with it. Obviously, all of the latter can have an impact on human physiology and even induce detrimental changes. Some organ systems have been studied thoroughly under space conditions, however, not much is known on the functional and morphological effects of spaceflight on the human central nervous system. Previous studies have already shown that central nervous system changes occur during and after spaceflight in the form of neurovestibular problems, alterations in cognitive function and sensory perception, cephalic fluid shifts and psychological disturbances. However, little is known about the underlying neural substrates. In this review, we discuss the current limited knowledge on neuroplastic changes in the human central nervous system associated with spaceflight (actual or simulated) as measured by magnetic resonance imaging-based techniques. Furthermore, we discuss these findings as well as their future perspectives, since this can encourage future research into this delicate and intriguing aspect of spaceflight. Currently, the literature suffers from heterogeneous experimental set-ups and therefore, the lack of comparability of findings among studies. However, the cerebellum, cortical sensorimotor and somatosensory areas and vestibular-related pathways seem to be involved across different studies, suggesting that these brain regions are most affected by (simulated) spaceflight. Extending this knowledge is crucial, especially with the eye on long-duration interplanetary missions (e.g. Mars) and space tourism.
format	article
author	Angelique Van Ombergen Steven Laureys Stefan Sunaert Elena Tomilovskaya Paul M. Parizel Floris L. Wuyts
author_facet	Angelique Van Ombergen Steven Laureys Stefan Sunaert Elena Tomilovskaya Paul M. Parizel Floris L. Wuyts
author_sort	Angelique Van Ombergen
title	Spaceflight-induced neuroplasticity in humans as measured by MRI: what do we know so far?
title_short	Spaceflight-induced neuroplasticity in humans as measured by MRI: what do we know so far?
title_full	Spaceflight-induced neuroplasticity in humans as measured by MRI: what do we know so far?
title_fullStr	Spaceflight-induced neuroplasticity in humans as measured by MRI: what do we know so far?
title_full_unstemmed	Spaceflight-induced neuroplasticity in humans as measured by MRI: what do we know so far?
title_sort	spaceflight-induced neuroplasticity in humans as measured by mri: what do we know so far?
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/db5151a5462b422b855f5cf9ecbc9c7f
work_keys_str_mv	AT angeliquevanombergen spaceflightinducedneuroplasticityinhumansasmeasuredbymriwhatdoweknowsofar AT stevenlaureys spaceflightinducedneuroplasticityinhumansasmeasuredbymriwhatdoweknowsofar AT stefansunaert spaceflightinducedneuroplasticityinhumansasmeasuredbymriwhatdoweknowsofar AT elenatomilovskaya spaceflightinducedneuroplasticityinhumansasmeasuredbymriwhatdoweknowsofar AT paulmparizel spaceflightinducedneuroplasticityinhumansasmeasuredbymriwhatdoweknowsofar AT florislwuyts spaceflightinducedneuroplasticityinhumansasmeasuredbymriwhatdoweknowsofar
_version_	1718395195209285632

Spaceflight-induced neuroplasticity in humans as measured by MRI: what do we know so far?

Ejemplares similares