Activation of ectopic olfactory receptor 544 induces GLP-1 secretion and regulates gut inflammation

Activation of ectopic olfactory receptor 544 induces GLP-1 secretion and regulates gut inflammation

Olfactory receptors are ectopically expressed in extra-nasal tissues. The gut is constantly exposed to high levels of odorants where ectopic olfactory receptors may play critical roles. Activation of ectopic olfactory receptor 544 (Olfr544) by azelaic acid (AzA), an Olfr544 ligand, reduces adiposity...

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Main Authors: Chunyan Wu, Mi-Young Jeong, Jung Yeon Kim, Giljae Lee, Ji-Sun Kim, Yu Eun Cheong, Hyena Kang, Chung Hwan Cho, Jimin Kim, Min Kyung Park, You Kyoung Shin, Kyoung Heon Kim, Geun Hee Seol, Seung Hoi Koo, GwangPyo Ko, Sung-Joon Lee
Format: article
Language:EN
Published: Taylor & Francis Group 2021
Subjects:
olfr544
ectopic olfactory receptor
glp-1
gut microbiome
metabolome
colonic inflammation
Diseases of the digestive system. Gastroenterology
RC799-869
Online Access:https://doaj.org/article/db55a877eea0458bbe368e938b3c7ecc
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https://doaj.org/article/db55a877eea0458bbe368e938b3c7ecc

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