Influence of genetic variants in type I interferon genes on melanoma survival and therapy.

Influence of genetic variants in type I interferon genes on melanoma survival and therapy.

Melanoma is an immunogenic tumor; however, the efficacy of immune-therapy shows large inter-individual variation with possible influence of background genetic variation. In this study we report the influence of genetic polymorphisms in the type I interferon gene cluster on chromosome 9p22 on melanom...

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Main Authors: Romina Elizabeth Lenci, Melanie Bevier, Andreas Brandt, Justo Lorenzo Bermejo, Antje Sucker, Iris Moll, Dolores Planelles, Celia Requena, Eduardo Nagore, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/db5682c8bc814c1e90cbaba79b51cd69
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