Correlation between basal antral follicle count and mean ovarian diameter with ovarian responsiveness in art cycles

BACKGROUND & OBJECTIVE: Since, ovarian response during assisted reproductive technology (ART) depends on ovarian reserve so it is important to evaluate ovarian reserve before the ART cycle. The purpose of this study was to determine correlation between basal antral follicle count and mean ovaria...

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Autores principales: Z Basirat, G Riazi Arasi, S Esmaeil Zadeh, M Zeinal Zadeh, T Nazari
Formato: article
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Publicado: Babol University of Medical Sciences 2006
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spelling oai:doaj.org-article:db5b69efb5f043a680d227349d1db2532021-11-10T09:12:49ZCorrelation between basal antral follicle count and mean ovarian diameter with ovarian responsiveness in art cycles1561-41072251-7170https://doaj.org/article/db5b69efb5f043a680d227349d1db2532006-06-01T00:00:00Zhttp://jbums.org/article-1-2528-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND & OBJECTIVE: Since, ovarian response during assisted reproductive technology (ART) depends on ovarian reserve so it is important to evaluate ovarian reserve before the ART cycle. The purpose of this study was to determine correlation between basal antral follicle count and mean ovarian diameter before treatment with ovarian responsiveness.METHODS: This study was performed on 94 infertile women who consecutively underwent ART in Fatemeh Zahra Center in Babol for one year. FSH, LH and FSH/LH were measured on day 3 of cycle, and basal antral follicle count and mean ovarian diameter were determined by vaginal sonography. GnRH Agonist was administered for hypophysial down regulation and then gonadotropin was administered for induction of ovulation. Ampules of gonodotropin, days of stimulation, numbers of oocytes, pregnancy rate and cycle cancellation were recorded. FINDINGS: A positive linear correlation was seen between basal antral follicle count with recovered oocytes (p<0.05). Also, pregnancy rate had a positive linear correlation with recovered oocyte, fertilized ovum and basal antral follicle count (p< 0.05). A negative linear correlation was observed between basal antral follicle count with ampules of gonadotropin, days of stimulation that was not statistically significant (p>0.05). It was not seen a significant correlation between mean ovarian diameter and pregnancy rate, recovered oocytes, days of stimulation and ampules of gonodotropin. CONCLUSION: The results show that antral follicle count on cycle day 3 has positive correlation with oocyte count and pregnancy rate. It is an easy and reliable method to predict ovarian responsiveness that allows physicians to evaluate patients immediately before ART stimulation and to optimize stimulation protocols.Z BasiratG Riazi ArasiS Esmaeil ZadehM Zeinal ZadehT NazariBabol University of Medical Sciencesarticleartbasal antral follicle countovarian diameter/sizepregnancy rateMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 8, Iss 3, Pp 13-18 (2006)
institution DOAJ
collection DOAJ
language EN
FA
topic art
basal antral follicle count
ovarian diameter/size
pregnancy rate
Medicine
R
Medicine (General)
R5-920
spellingShingle art
basal antral follicle count
ovarian diameter/size
pregnancy rate
Medicine
R
Medicine (General)
R5-920
Z Basirat
G Riazi Arasi
S Esmaeil Zadeh
M Zeinal Zadeh
T Nazari
Correlation between basal antral follicle count and mean ovarian diameter with ovarian responsiveness in art cycles
description BACKGROUND & OBJECTIVE: Since, ovarian response during assisted reproductive technology (ART) depends on ovarian reserve so it is important to evaluate ovarian reserve before the ART cycle. The purpose of this study was to determine correlation between basal antral follicle count and mean ovarian diameter before treatment with ovarian responsiveness.METHODS: This study was performed on 94 infertile women who consecutively underwent ART in Fatemeh Zahra Center in Babol for one year. FSH, LH and FSH/LH were measured on day 3 of cycle, and basal antral follicle count and mean ovarian diameter were determined by vaginal sonography. GnRH Agonist was administered for hypophysial down regulation and then gonadotropin was administered for induction of ovulation. Ampules of gonodotropin, days of stimulation, numbers of oocytes, pregnancy rate and cycle cancellation were recorded. FINDINGS: A positive linear correlation was seen between basal antral follicle count with recovered oocytes (p<0.05). Also, pregnancy rate had a positive linear correlation with recovered oocyte, fertilized ovum and basal antral follicle count (p< 0.05). A negative linear correlation was observed between basal antral follicle count with ampules of gonadotropin, days of stimulation that was not statistically significant (p>0.05). It was not seen a significant correlation between mean ovarian diameter and pregnancy rate, recovered oocytes, days of stimulation and ampules of gonodotropin. CONCLUSION: The results show that antral follicle count on cycle day 3 has positive correlation with oocyte count and pregnancy rate. It is an easy and reliable method to predict ovarian responsiveness that allows physicians to evaluate patients immediately before ART stimulation and to optimize stimulation protocols.
format article
author Z Basirat
G Riazi Arasi
S Esmaeil Zadeh
M Zeinal Zadeh
T Nazari
author_facet Z Basirat
G Riazi Arasi
S Esmaeil Zadeh
M Zeinal Zadeh
T Nazari
author_sort Z Basirat
title Correlation between basal antral follicle count and mean ovarian diameter with ovarian responsiveness in art cycles
title_short Correlation between basal antral follicle count and mean ovarian diameter with ovarian responsiveness in art cycles
title_full Correlation between basal antral follicle count and mean ovarian diameter with ovarian responsiveness in art cycles
title_fullStr Correlation between basal antral follicle count and mean ovarian diameter with ovarian responsiveness in art cycles
title_full_unstemmed Correlation between basal antral follicle count and mean ovarian diameter with ovarian responsiveness in art cycles
title_sort correlation between basal antral follicle count and mean ovarian diameter with ovarian responsiveness in art cycles
publisher Babol University of Medical Sciences
publishDate 2006
url https://doaj.org/article/db5b69efb5f043a680d227349d1db253
work_keys_str_mv AT zbasirat correlationbetweenbasalantralfolliclecountandmeanovariandiameterwithovarianresponsivenessinartcycles
AT griaziarasi correlationbetweenbasalantralfolliclecountandmeanovariandiameterwithovarianresponsivenessinartcycles
AT sesmaeilzadeh correlationbetweenbasalantralfolliclecountandmeanovariandiameterwithovarianresponsivenessinartcycles
AT mzeinalzadeh correlationbetweenbasalantralfolliclecountandmeanovariandiameterwithovarianresponsivenessinartcycles
AT tnazari correlationbetweenbasalantralfolliclecountandmeanovariandiameterwithovarianresponsivenessinartcycles
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