SALIVARY ALKALINE PHOSPHATASE ACTIVITY AND INORGANIC PHOSPHORUS CONCENTRATION IN CHILDREN WITH DIFFERENT DENTAL CARIES

BACKGROUND AND OBJECTIVE: Dental caries is the most common dental disease in children. Alkaline phosphatase (ALP) activity and inorganic phosphorus concentration in saliva may be related to the susceptibility to dental caries.METHODS: In this case-control study, one hundred children in the age group...

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Autores principales: S Mahjoub, M Ghasempour, I Mohammadi
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Publicado: Babol University of Medical Sciences 2007
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spelling oai:doaj.org-article:db5ccfe03db24128a3049e6651638c4b2021-11-10T09:10:17ZSALIVARY ALKALINE PHOSPHATASE ACTIVITY AND INORGANIC PHOSPHORUS CONCENTRATION IN CHILDREN WITH DIFFERENT DENTAL CARIES1561-41072251-7170https://doaj.org/article/db5ccfe03db24128a3049e6651638c4b2007-10-01T00:00:00Zhttp://jbums.org/article-1-2518-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Dental caries is the most common dental disease in children. Alkaline phosphatase (ALP) activity and inorganic phosphorus concentration in saliva may be related to the susceptibility to dental caries.METHODS: In this case-control study, one hundred children in the age group of 4 – 6 years were divided into 3 groups: group one, 30 caries– free children with dfs <1, group two, 33 children with 5< dfs ≤10 and group three, 37 children with dfs> 10. The unstimulated mixed salivary sample was collected from each child. After centrifuge, supernatants were separated and measurements of salivary ALP activity and inorganic phosphorus concentration were performed by using colorimetric techniques. Data were analyzed by SPSS software and student t-test. FINDINGS: Mean of dfs in groups 1, 2 and 3 were 0.36, 7.12 and 16.32, respectively. Mean values of ALP activity in group 2 (16.9 IU/L) and group 3 (18.3 IU/L) were significantly higher than group 1 (5.4 IU/L) (p<0.05). In addition, mean values of inorganic phosphorus in group 2 (31.1mg/dl) and group 3 (29.3mg/dl) were significantly higher than group 1 (16.2mg/dl) (p< 0.05).CONCLUSION: Our results revealed that ALP activity and inorganic phosphorus concentration had a direct relationship with the increase in caries rates. But this relationship was not seen between moderate and severe caries.S MahjoubM Ghasempour,I MohammadiBabol University of Medical Sciencesarticlealkaline phosphataseinorganic phosphorusdental cariessalivaMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 9, Iss 4, Pp 23-28 (2007)
institution DOAJ
collection DOAJ
language EN
FA
topic alkaline phosphatase
inorganic phosphorus
dental caries
saliva
Medicine
R
Medicine (General)
R5-920
spellingShingle alkaline phosphatase
inorganic phosphorus
dental caries
saliva
Medicine
R
Medicine (General)
R5-920
S Mahjoub
M Ghasempour,
I Mohammadi
SALIVARY ALKALINE PHOSPHATASE ACTIVITY AND INORGANIC PHOSPHORUS CONCENTRATION IN CHILDREN WITH DIFFERENT DENTAL CARIES
description BACKGROUND AND OBJECTIVE: Dental caries is the most common dental disease in children. Alkaline phosphatase (ALP) activity and inorganic phosphorus concentration in saliva may be related to the susceptibility to dental caries.METHODS: In this case-control study, one hundred children in the age group of 4 – 6 years were divided into 3 groups: group one, 30 caries– free children with dfs <1, group two, 33 children with 5< dfs ≤10 and group three, 37 children with dfs> 10. The unstimulated mixed salivary sample was collected from each child. After centrifuge, supernatants were separated and measurements of salivary ALP activity and inorganic phosphorus concentration were performed by using colorimetric techniques. Data were analyzed by SPSS software and student t-test. FINDINGS: Mean of dfs in groups 1, 2 and 3 were 0.36, 7.12 and 16.32, respectively. Mean values of ALP activity in group 2 (16.9 IU/L) and group 3 (18.3 IU/L) were significantly higher than group 1 (5.4 IU/L) (p<0.05). In addition, mean values of inorganic phosphorus in group 2 (31.1mg/dl) and group 3 (29.3mg/dl) were significantly higher than group 1 (16.2mg/dl) (p< 0.05).CONCLUSION: Our results revealed that ALP activity and inorganic phosphorus concentration had a direct relationship with the increase in caries rates. But this relationship was not seen between moderate and severe caries.
format article
author S Mahjoub
M Ghasempour,
I Mohammadi
author_facet S Mahjoub
M Ghasempour,
I Mohammadi
author_sort S Mahjoub
title SALIVARY ALKALINE PHOSPHATASE ACTIVITY AND INORGANIC PHOSPHORUS CONCENTRATION IN CHILDREN WITH DIFFERENT DENTAL CARIES
title_short SALIVARY ALKALINE PHOSPHATASE ACTIVITY AND INORGANIC PHOSPHORUS CONCENTRATION IN CHILDREN WITH DIFFERENT DENTAL CARIES
title_full SALIVARY ALKALINE PHOSPHATASE ACTIVITY AND INORGANIC PHOSPHORUS CONCENTRATION IN CHILDREN WITH DIFFERENT DENTAL CARIES
title_fullStr SALIVARY ALKALINE PHOSPHATASE ACTIVITY AND INORGANIC PHOSPHORUS CONCENTRATION IN CHILDREN WITH DIFFERENT DENTAL CARIES
title_full_unstemmed SALIVARY ALKALINE PHOSPHATASE ACTIVITY AND INORGANIC PHOSPHORUS CONCENTRATION IN CHILDREN WITH DIFFERENT DENTAL CARIES
title_sort salivary alkaline phosphatase activity and inorganic phosphorus concentration in children with different dental caries
publisher Babol University of Medical Sciences
publishDate 2007
url https://doaj.org/article/db5ccfe03db24128a3049e6651638c4b
work_keys_str_mv AT smahjoub salivaryalkalinephosphataseactivityandinorganicphosphorusconcentrationinchildrenwithdifferentdentalcaries
AT mghasempour salivaryalkalinephosphataseactivityandinorganicphosphorusconcentrationinchildrenwithdifferentdentalcaries
AT imohammadi salivaryalkalinephosphataseactivityandinorganicphosphorusconcentrationinchildrenwithdifferentdentalcaries
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