G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination

The molecular mechanism controlling oligodendrocyte differentiation is not fully understood. Here the authors show that G protein coupled receptor 37 acts as a negative regulator of CNS myelination, and this effect is mediated by suppression of ERK signalling.

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Autores principales:	Hyun-Jeong Yang, Anna Vainshtein, Galia Maik-Rachline, Elior Peles
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/db5fa7523f93429b9dcb729dec275fe0
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spelling	oai:doaj.org-article:db5fa7523f93429b9dcb729dec275fe02021-12-02T16:49:41ZG protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination10.1038/ncomms108842041-1723https://doaj.org/article/db5fa7523f93429b9dcb729dec275fe02016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10884https://doaj.org/toc/2041-1723The molecular mechanism controlling oligodendrocyte differentiation is not fully understood. Here the authors show that G protein coupled receptor 37 acts as a negative regulator of CNS myelination, and this effect is mediated by suppression of ERK signalling.Hyun-Jeong YangAnna VainshteinGalia Maik-RachlineElior PelesNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hyun-Jeong Yang Anna Vainshtein Galia Maik-Rachline Elior Peles G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination
description	The molecular mechanism controlling oligodendrocyte differentiation is not fully understood. Here the authors show that G protein coupled receptor 37 acts as a negative regulator of CNS myelination, and this effect is mediated by suppression of ERK signalling.
format	article
author	Hyun-Jeong Yang Anna Vainshtein Galia Maik-Rachline Elior Peles
author_facet	Hyun-Jeong Yang Anna Vainshtein Galia Maik-Rachline Elior Peles
author_sort	Hyun-Jeong Yang
title	G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination
title_short	G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination
title_full	G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination
title_fullStr	G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination
title_full_unstemmed	G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination
title_sort	g protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/db5fa7523f93429b9dcb729dec275fe0
work_keys_str_mv	AT hyunjeongyang gproteincoupledreceptor37isanegativeregulatorofoligodendrocytedifferentiationandmyelination AT annavainshtein gproteincoupledreceptor37isanegativeregulatorofoligodendrocytedifferentiationandmyelination AT galiamaikrachline gproteincoupledreceptor37isanegativeregulatorofoligodendrocytedifferentiationandmyelination AT eliorpeles gproteincoupledreceptor37isanegativeregulatorofoligodendrocytedifferentiationandmyelination
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G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination

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