G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination

G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination

The molecular mechanism controlling oligodendrocyte differentiation is not fully understood. Here the authors show that G protein coupled receptor 37 acts as a negative regulator of CNS myelination, and this effect is mediated by suppression of ERK signalling.

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Detalles Bibliográficos
Autores principales: Hyun-Jeong Yang, Anna Vainshtein, Galia Maik-Rachline, Elior Peles
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/db5fa7523f93429b9dcb729dec275fe0
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