G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination
The molecular mechanism controlling oligodendrocyte differentiation is not fully understood. Here the authors show that G protein coupled receptor 37 acts as a negative regulator of CNS myelination, and this effect is mediated by suppression of ERK signalling.
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Auteurs principaux: | Hyun-Jeong Yang, Anna Vainshtein, Galia Maik-Rachline, Elior Peles |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2016
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Sujets: | |
Accès en ligne: | https://doaj.org/article/db5fa7523f93429b9dcb729dec275fe0 |
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