G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination

The molecular mechanism controlling oligodendrocyte differentiation is not fully understood. Here the authors show that G protein coupled receptor 37 acts as a negative regulator of CNS myelination, and this effect is mediated by suppression of ERK signalling.

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Auteurs principaux: Hyun-Jeong Yang, Anna Vainshtein, Galia Maik-Rachline, Elior Peles
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/db5fa7523f93429b9dcb729dec275fe0
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