PEM anchorage on titanium using catechol grafting.

<h4>Background</h4>This study deals with the anchorage of polyelectrolyte films onto titanium surfaces via a cathecol-based linker for biomedical applications.<h4>Methodology</h4>The following study uses a molecule functionalized with a catechol and a carboxylic acid: 3-(3,4-...

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Autores principales: Hélène Marie, Amélie Barrere, Frederic Schoenstein, Marie-Hélène Chavanne, Brigitte Grosgogeat, Laurence Mora
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/db79ca63459b4e1096550aaa5b4afb02
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Sumario:<h4>Background</h4>This study deals with the anchorage of polyelectrolyte films onto titanium surfaces via a cathecol-based linker for biomedical applications.<h4>Methodology</h4>The following study uses a molecule functionalized with a catechol and a carboxylic acid: 3-(3,4-dihydroxyphenyl)propanoic acid. This molecule is anchored to the TiO(2) substrate via the catechol while the carboxylic acid reacts with polymers bearing amine groups. By providing a film anchorage of chemisorption type, it makes possible to deposit polyelectrolytes on the surface of titanium.<h4>Principal findings</h4>Infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectroscopy (XPS), contact angle and atomic force microscopy (AFM) measurements show that the different steps of grafting have been successfully performed.<h4>Conclusions</h4>This method based on catechol anchorage of polyelectrolytes open a window towards large possibilities of clinical applications.