Destabilization of the outer and inner mitochondrial membranes by core and linker histones.

Destabilization of the outer and inner mitochondrial membranes by core and linker histones.

<h4>Background</h4>Extensive DNA damage leads to apoptosis. Histones play a central role in DNA damage sensing and may mediate signals of genotoxic damage to cytosolic effectors including mitochondria.<h4>Methodology/principal findings</h4>We have investigated the effects of...

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Autores principales: Annunziata Cascone, Celine Bruelle, Dan Lindholm, Paolo Bernardi, Ove Eriksson
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/db81b922028b4698be8b8a5c99af8b66
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