Clinical and hospitalisation predictors of COVID-19 in the first month of the pandemic, Portugal

COVID-19 mainly presents as a respiratory disease with flu‐like symptoms, however, recent findings suggest that non-respiratory symptoms can occur early in the infection and cluster together in different groups in different regions. We collected surveillance data among COVID-19 suspected cases teste...

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Autores principales:	Mariana Perez Duque, Neil J. Saad, Héloïse Lucaccioni, Cristina Costa, Geroid McMahon, Firmino Machado, Sooria Balasegaram, Rita Sá Machado
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/db8edb34268340b8a8aaf8935ea750d7
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spelling	oai:doaj.org-article:db8edb34268340b8a8aaf8935ea750d72021-11-25T06:19:27ZClinical and hospitalisation predictors of COVID-19 in the first month of the pandemic, Portugal1932-6203https://doaj.org/article/db8edb34268340b8a8aaf8935ea750d72021-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604361/?tool=EBIhttps://doaj.org/toc/1932-6203COVID-19 mainly presents as a respiratory disease with flu‐like symptoms, however, recent findings suggest that non-respiratory symptoms can occur early in the infection and cluster together in different groups in different regions. We collected surveillance data among COVID-19 suspected cases tested in mainland Portugal during the first wave of the pandemic, March-April 2020. A multivariable logistic-regression analysis was performed to ascertain the effects of age, sex, prior medical condition and symptoms on the likelihood of testing positive and hospitalisation. Of 25,926 COVID-19 suspected cases included in this study, 5,298 (20%) tested positive. Symptoms were grouped into ten clusters, of which two main ones: one with cough and fever and another with the remainder. There was a higher odds of a positive test with increasing age, myalgia and headache. The odds of being hospitalised increased with age, presence of fever, dyspnoea, or having a prior medical condition although these results varied by region. Presence of cough and other respiratory symptoms did not predict COVID-19 compared to non-COVID respiratory disease patients in any region. Dyspnoea was a strong determinant of hospitalisation, as well as fever and the presence of a prior medical condition, whereas these results varied by region.Mariana Perez DuqueNeil J. SaadHéloïse LucaccioniCristina CostaGeroid McMahonFirmino MachadoSooria BalasegaramRita Sá MachadoPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mariana Perez Duque Neil J. Saad Héloïse Lucaccioni Cristina Costa Geroid McMahon Firmino Machado Sooria Balasegaram Rita Sá Machado Clinical and hospitalisation predictors of COVID-19 in the first month of the pandemic, Portugal
description	COVID-19 mainly presents as a respiratory disease with flu‐like symptoms, however, recent findings suggest that non-respiratory symptoms can occur early in the infection and cluster together in different groups in different regions. We collected surveillance data among COVID-19 suspected cases tested in mainland Portugal during the first wave of the pandemic, March-April 2020. A multivariable logistic-regression analysis was performed to ascertain the effects of age, sex, prior medical condition and symptoms on the likelihood of testing positive and hospitalisation. Of 25,926 COVID-19 suspected cases included in this study, 5,298 (20%) tested positive. Symptoms were grouped into ten clusters, of which two main ones: one with cough and fever and another with the remainder. There was a higher odds of a positive test with increasing age, myalgia and headache. The odds of being hospitalised increased with age, presence of fever, dyspnoea, or having a prior medical condition although these results varied by region. Presence of cough and other respiratory symptoms did not predict COVID-19 compared to non-COVID respiratory disease patients in any region. Dyspnoea was a strong determinant of hospitalisation, as well as fever and the presence of a prior medical condition, whereas these results varied by region.
format	article
author	Mariana Perez Duque Neil J. Saad Héloïse Lucaccioni Cristina Costa Geroid McMahon Firmino Machado Sooria Balasegaram Rita Sá Machado
author_facet	Mariana Perez Duque Neil J. Saad Héloïse Lucaccioni Cristina Costa Geroid McMahon Firmino Machado Sooria Balasegaram Rita Sá Machado
author_sort	Mariana Perez Duque
title	Clinical and hospitalisation predictors of COVID-19 in the first month of the pandemic, Portugal
title_short	Clinical and hospitalisation predictors of COVID-19 in the first month of the pandemic, Portugal
title_full	Clinical and hospitalisation predictors of COVID-19 in the first month of the pandemic, Portugal
title_fullStr	Clinical and hospitalisation predictors of COVID-19 in the first month of the pandemic, Portugal
title_full_unstemmed	Clinical and hospitalisation predictors of COVID-19 in the first month of the pandemic, Portugal
title_sort	clinical and hospitalisation predictors of covid-19 in the first month of the pandemic, portugal
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/db8edb34268340b8a8aaf8935ea750d7
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Clinical and hospitalisation predictors of COVID-19 in the first month of the pandemic, Portugal

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