A connexin30 mutation rescues hearing and reveals roles for gap junctions in cochlear amplification and micromechanics

A point mutation in the gap-junction protein connexin 30 stops early onset age-related hearing loss. Here, the authors show that gap junctions contribute to cochlear micromechanics and that cochlear amplification is likely controlled by extracellular potentials in vicinity of the cochlear sensory ce...

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Autores principales:	Victoria A. Lukashkina, Snezana Levic, Andrei N. Lukashkin, Nicola Strenzke, Ian J. Russell
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/db9279e8479c4eafbe4a3235a3fa6f72
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spelling	oai:doaj.org-article:db9279e8479c4eafbe4a3235a3fa6f722021-12-02T17:06:07ZA connexin30 mutation rescues hearing and reveals roles for gap junctions in cochlear amplification and micromechanics10.1038/ncomms145302041-1723https://doaj.org/article/db9279e8479c4eafbe4a3235a3fa6f722017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14530https://doaj.org/toc/2041-1723A point mutation in the gap-junction protein connexin 30 stops early onset age-related hearing loss. Here, the authors show that gap junctions contribute to cochlear micromechanics and that cochlear amplification is likely controlled by extracellular potentials in vicinity of the cochlear sensory cells.Victoria A. LukashkinaSnezana LevicAndrei N. LukashkinNicola StrenzkeIan J. RussellNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Victoria A. Lukashkina Snezana Levic Andrei N. Lukashkin Nicola Strenzke Ian J. Russell A connexin30 mutation rescues hearing and reveals roles for gap junctions in cochlear amplification and micromechanics
description	A point mutation in the gap-junction protein connexin 30 stops early onset age-related hearing loss. Here, the authors show that gap junctions contribute to cochlear micromechanics and that cochlear amplification is likely controlled by extracellular potentials in vicinity of the cochlear sensory cells.
format	article
author	Victoria A. Lukashkina Snezana Levic Andrei N. Lukashkin Nicola Strenzke Ian J. Russell
author_facet	Victoria A. Lukashkina Snezana Levic Andrei N. Lukashkin Nicola Strenzke Ian J. Russell
author_sort	Victoria A. Lukashkina
title	A connexin30 mutation rescues hearing and reveals roles for gap junctions in cochlear amplification and micromechanics
title_short	A connexin30 mutation rescues hearing and reveals roles for gap junctions in cochlear amplification and micromechanics
title_full	A connexin30 mutation rescues hearing and reveals roles for gap junctions in cochlear amplification and micromechanics
title_fullStr	A connexin30 mutation rescues hearing and reveals roles for gap junctions in cochlear amplification and micromechanics
title_full_unstemmed	A connexin30 mutation rescues hearing and reveals roles for gap junctions in cochlear amplification and micromechanics
title_sort	connexin30 mutation rescues hearing and reveals roles for gap junctions in cochlear amplification and micromechanics
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/db9279e8479c4eafbe4a3235a3fa6f72
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A connexin30 mutation rescues hearing and reveals roles for gap junctions in cochlear amplification and micromechanics

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