Lobular architecture of human adipose tissue defines the niche and fate of progenitor cells

In human adipose tissue (AT), adipocytes are organized into units of lobules. Here the authors identify distinct fibrous septal and stromal compartments within AT lobules that differ in composition and potential between subcutaneous and visceral regions and are disturbed in obesity and metabolic syn...

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Auteurs principaux: D. Estève, N. Boulet, C. Belles, A. Zakaroff-Girard, P. Decaunes, A. Briot, Y. Veeranagouda, M. Didier, A. Remaury, J. C. Guillemot, S. Ledoux, C. Dani, A. Bouloumié, J. Galitzky
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/dba09988bc1e42c79fc9d479582cd049
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Résumé:In human adipose tissue (AT), adipocytes are organized into units of lobules. Here the authors identify distinct fibrous septal and stromal compartments within AT lobules that differ in composition and potential between subcutaneous and visceral regions and are disturbed in obesity and metabolic syndrome.