Lobular architecture of human adipose tissue defines the niche and fate of progenitor cells

In human adipose tissue (AT), adipocytes are organized into units of lobules. Here the authors identify distinct fibrous septal and stromal compartments within AT lobules that differ in composition and potential between subcutaneous and visceral regions and are disturbed in obesity and metabolic syn...

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Autores principales: D. Estève, N. Boulet, C. Belles, A. Zakaroff-Girard, P. Decaunes, A. Briot, Y. Veeranagouda, M. Didier, A. Remaury, J. C. Guillemot, S. Ledoux, C. Dani, A. Bouloumié, J. Galitzky
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/dba09988bc1e42c79fc9d479582cd049
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Sumario:In human adipose tissue (AT), adipocytes are organized into units of lobules. Here the authors identify distinct fibrous septal and stromal compartments within AT lobules that differ in composition and potential between subcutaneous and visceral regions and are disturbed in obesity and metabolic syndrome.