Community oncologists’ perceptions and utilization of large-panel genomic tumor testing

Abstract Purpose Large-panel genomic tumor testing (GTT) is an emerging technology with great promise but uncertain clinical value. Previous research has documented variability in academic oncologists’ perceptions and use of GTT, but little is known about community oncologists’ perceptions of GTT an...

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Autores principales:	Eric C. Anderson, Alexandra C. Hinton, Christine W. Lary, Anny T. H. R. Fenton, Andrey Antov, Emily Edelman, Petra Helbig, Kate Reed, Susan Miesfeldt, Christian A. Thomas, Michael J. Hall, J. Scott Roberts, Jens Rueter, Paul K. J. Han, MCGI Working Group
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Genomic Cancer Uncertainty Attitudes Confidence Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/dbabf7f6cf97472f85681b1a23bd2da2
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spelling	oai:doaj.org-article:dbabf7f6cf97472f85681b1a23bd2da22021-11-28T12:27:49ZCommunity oncologists’ perceptions and utilization of large-panel genomic tumor testing10.1186/s12885-021-08985-01471-2407https://doaj.org/article/dbabf7f6cf97472f85681b1a23bd2da22021-11-01T00:00:00Zhttps://doi.org/10.1186/s12885-021-08985-0https://doaj.org/toc/1471-2407Abstract Purpose Large-panel genomic tumor testing (GTT) is an emerging technology with great promise but uncertain clinical value. Previous research has documented variability in academic oncologists’ perceptions and use of GTT, but little is known about community oncologists’ perceptions of GTT and how perceptions relate to clinicians' intentions to use GTT. Methods Community oncology physicians (N = 58) participating in a statewide initiative aimed at improving access to large-panel GTT completed surveys assessing their confidence in using GTT, attitudes regarding the value of GTT, perceptions of barriers to GTT implementation, and future intentions to use GTTs. Descriptive and multivariable regression analyses were conducted to characterize these perceptions and to explore the relationships between them. Results There was substantial variability in clinicians’ perceptions of GTT. Clinicians generally had moderate confidence in their ability to use GTT, but lower confidence in patients’ ability to understand test results and access targeted treatment. Clinicians had positive attitudes regarding the value of GTT. Clinicians’ future intentions to use GTT were associated with greater confidence in using GTT and greater perceived barriers to implementing GTT, but not with attitudes about the value of GTT. Conclusions Community oncologists’ perceptions of large-panel genomic tumor testing are variable, and their future intentions to use GTT are associated with both their confidence in and perceived barriers to its use, but not with their attitudes towards GTT. More research is needed to understand other factors that determine how oncologists perceive and use GTT in clinical practice.Eric C. AndersonAlexandra C. HintonChristine W. LaryAnny T. H. R. FentonAndrey AntovEmily EdelmanPetra HelbigKate ReedSusan MiesfeldtChristian A. ThomasMichael J. HallJ. Scott RobertsJens RueterPaul K. J. HanMCGI Working GroupBMCarticleGenomicCancerUncertaintyAttitudesConfidenceNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENBMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Genomic Cancer Uncertainty Attitudes Confidence Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	Genomic Cancer Uncertainty Attitudes Confidence Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Eric C. Anderson Alexandra C. Hinton Christine W. Lary Anny T. H. R. Fenton Andrey Antov Emily Edelman Petra Helbig Kate Reed Susan Miesfeldt Christian A. Thomas Michael J. Hall J. Scott Roberts Jens Rueter Paul K. J. Han MCGI Working Group Community oncologists’ perceptions and utilization of large-panel genomic tumor testing
description	Abstract Purpose Large-panel genomic tumor testing (GTT) is an emerging technology with great promise but uncertain clinical value. Previous research has documented variability in academic oncologists’ perceptions and use of GTT, but little is known about community oncologists’ perceptions of GTT and how perceptions relate to clinicians' intentions to use GTT. Methods Community oncology physicians (N = 58) participating in a statewide initiative aimed at improving access to large-panel GTT completed surveys assessing their confidence in using GTT, attitudes regarding the value of GTT, perceptions of barriers to GTT implementation, and future intentions to use GTTs. Descriptive and multivariable regression analyses were conducted to characterize these perceptions and to explore the relationships between them. Results There was substantial variability in clinicians’ perceptions of GTT. Clinicians generally had moderate confidence in their ability to use GTT, but lower confidence in patients’ ability to understand test results and access targeted treatment. Clinicians had positive attitudes regarding the value of GTT. Clinicians’ future intentions to use GTT were associated with greater confidence in using GTT and greater perceived barriers to implementing GTT, but not with attitudes about the value of GTT. Conclusions Community oncologists’ perceptions of large-panel genomic tumor testing are variable, and their future intentions to use GTT are associated with both their confidence in and perceived barriers to its use, but not with their attitudes towards GTT. More research is needed to understand other factors that determine how oncologists perceive and use GTT in clinical practice.
format	article
author	Eric C. Anderson Alexandra C. Hinton Christine W. Lary Anny T. H. R. Fenton Andrey Antov Emily Edelman Petra Helbig Kate Reed Susan Miesfeldt Christian A. Thomas Michael J. Hall J. Scott Roberts Jens Rueter Paul K. J. Han MCGI Working Group
author_facet	Eric C. Anderson Alexandra C. Hinton Christine W. Lary Anny T. H. R. Fenton Andrey Antov Emily Edelman Petra Helbig Kate Reed Susan Miesfeldt Christian A. Thomas Michael J. Hall J. Scott Roberts Jens Rueter Paul K. J. Han MCGI Working Group
author_sort	Eric C. Anderson
title	Community oncologists’ perceptions and utilization of large-panel genomic tumor testing
title_short	Community oncologists’ perceptions and utilization of large-panel genomic tumor testing
title_full	Community oncologists’ perceptions and utilization of large-panel genomic tumor testing
title_fullStr	Community oncologists’ perceptions and utilization of large-panel genomic tumor testing
title_full_unstemmed	Community oncologists’ perceptions and utilization of large-panel genomic tumor testing
title_sort	community oncologists’ perceptions and utilization of large-panel genomic tumor testing
publisher	BMC
publishDate	2021
url	https://doaj.org/article/dbabf7f6cf97472f85681b1a23bd2da2
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Community oncologists’ perceptions and utilization of large-panel genomic tumor testing

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