Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species

The role of reactive oxygen species (ROS) in signalling and specific targets is not fully understood. Here the authors perform a global proteomic analysis to delineate the yeast redoxome and show that increased levels of intracellular ROS caused by dysfunctional mitochondria decrease global protein...

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Autores principales:	Ulrike Topf, Ida Suppanz, Lukasz Samluk, Lidia Wrobel, Alexander Böser, Paulina Sakowska, Bettina Knapp, Martyna K. Pietrzyk, Agnieszka Chacinska, Bettina Warscheid
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/dbae8e44a79e41df9b1f9b615b6f8901
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spelling	oai:doaj.org-article:dbae8e44a79e41df9b1f9b615b6f89012021-12-02T16:49:20ZQuantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species10.1038/s41467-017-02694-82041-1723https://doaj.org/article/dbae8e44a79e41df9b1f9b615b6f89012018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02694-8https://doaj.org/toc/2041-1723The role of reactive oxygen species (ROS) in signalling and specific targets is not fully understood. Here the authors perform a global proteomic analysis to delineate the yeast redoxome and show that increased levels of intracellular ROS caused by dysfunctional mitochondria decrease global protein synthesis.Ulrike TopfIda SuppanzLukasz SamlukLidia WrobelAlexander BöserPaulina SakowskaBettina KnappMartyna K. PietrzykAgnieszka ChacinskaBettina WarscheidNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ulrike Topf Ida Suppanz Lukasz Samluk Lidia Wrobel Alexander Böser Paulina Sakowska Bettina Knapp Martyna K. Pietrzyk Agnieszka Chacinska Bettina Warscheid Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species
description	The role of reactive oxygen species (ROS) in signalling and specific targets is not fully understood. Here the authors perform a global proteomic analysis to delineate the yeast redoxome and show that increased levels of intracellular ROS caused by dysfunctional mitochondria decrease global protein synthesis.
format	article
author	Ulrike Topf Ida Suppanz Lukasz Samluk Lidia Wrobel Alexander Böser Paulina Sakowska Bettina Knapp Martyna K. Pietrzyk Agnieszka Chacinska Bettina Warscheid
author_facet	Ulrike Topf Ida Suppanz Lukasz Samluk Lidia Wrobel Alexander Böser Paulina Sakowska Bettina Knapp Martyna K. Pietrzyk Agnieszka Chacinska Bettina Warscheid
author_sort	Ulrike Topf
title	Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species
title_short	Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species
title_full	Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species
title_fullStr	Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species
title_full_unstemmed	Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species
title_sort	quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/dbae8e44a79e41df9b1f9b615b6f8901
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Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species

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